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Severe Enteritis as the Sole Manifestation of Novel Coronavirus Disease 2019 (COVID-19) in Adolescent Patients

Enteritis as the only manifestation of novel coronavirus disease 2019 (COVID-19) in adolescents without features of multisystem inflammatory syndrome in children (MIS-C) or a prior history of inflammatory bowel disease (IBD) has not been described. We report two adolescent patients (a 14-year-old ma...

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Autores principales: Gupta, Sandeep, Kaushik, Ashlesha, Kest, Helen, Charles, Alexandra K., De Bruin, William, Colletti, Mario, Goldberg, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771253/
https://www.ncbi.nlm.nih.gov/pubmed/33425408
http://dx.doi.org/10.1155/2020/8823622
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author Gupta, Sandeep
Kaushik, Ashlesha
Kest, Helen
Charles, Alexandra K.
De Bruin, William
Colletti, Mario
Goldberg, David
author_facet Gupta, Sandeep
Kaushik, Ashlesha
Kest, Helen
Charles, Alexandra K.
De Bruin, William
Colletti, Mario
Goldberg, David
author_sort Gupta, Sandeep
collection PubMed
description Enteritis as the only manifestation of novel coronavirus disease 2019 (COVID-19) in adolescents without features of multisystem inflammatory syndrome in children (MIS-C) or a prior history of inflammatory bowel disease (IBD) has not been described. We report two adolescent patients (a 14-year-old male and a 20-year-old pregnant female) presenting to tertiary-care centers in the United States with severe enteritis as the only manifestation of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The patients were hospitalized with acute abdominal pain and gastrointestinal (GI) bleeding, with no evidence of MIS-C, and were previously healthy with no history of IBD. The patients' nasopharyngeal swabs were positive for SARS-CoV-2 infection by reverse transcription polymerase chain reaction (RT-PCR), and testing for other infectious etiologies was negative. Both patients received intravenous corticosteroids and recovered without short-term complications. None of the patients died. This report highlights the need for keeping a high index of suspicion for SARS-CoV-2 infection in adolescents presenting solely with gastrointestinal manifestations, in the absence of respiratory symptoms or multisystem involvement, for prompt recognition and timely management.
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spelling pubmed-77712532021-01-08 Severe Enteritis as the Sole Manifestation of Novel Coronavirus Disease 2019 (COVID-19) in Adolescent Patients Gupta, Sandeep Kaushik, Ashlesha Kest, Helen Charles, Alexandra K. De Bruin, William Colletti, Mario Goldberg, David Case Rep Infect Dis Case Report Enteritis as the only manifestation of novel coronavirus disease 2019 (COVID-19) in adolescents without features of multisystem inflammatory syndrome in children (MIS-C) or a prior history of inflammatory bowel disease (IBD) has not been described. We report two adolescent patients (a 14-year-old male and a 20-year-old pregnant female) presenting to tertiary-care centers in the United States with severe enteritis as the only manifestation of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The patients were hospitalized with acute abdominal pain and gastrointestinal (GI) bleeding, with no evidence of MIS-C, and were previously healthy with no history of IBD. The patients' nasopharyngeal swabs were positive for SARS-CoV-2 infection by reverse transcription polymerase chain reaction (RT-PCR), and testing for other infectious etiologies was negative. Both patients received intravenous corticosteroids and recovered without short-term complications. None of the patients died. This report highlights the need for keeping a high index of suspicion for SARS-CoV-2 infection in adolescents presenting solely with gastrointestinal manifestations, in the absence of respiratory symptoms or multisystem involvement, for prompt recognition and timely management. Hindawi 2020-12-23 /pmc/articles/PMC7771253/ /pubmed/33425408 http://dx.doi.org/10.1155/2020/8823622 Text en Copyright © 2020 Sandeep Gupta et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gupta, Sandeep
Kaushik, Ashlesha
Kest, Helen
Charles, Alexandra K.
De Bruin, William
Colletti, Mario
Goldberg, David
Severe Enteritis as the Sole Manifestation of Novel Coronavirus Disease 2019 (COVID-19) in Adolescent Patients
title Severe Enteritis as the Sole Manifestation of Novel Coronavirus Disease 2019 (COVID-19) in Adolescent Patients
title_full Severe Enteritis as the Sole Manifestation of Novel Coronavirus Disease 2019 (COVID-19) in Adolescent Patients
title_fullStr Severe Enteritis as the Sole Manifestation of Novel Coronavirus Disease 2019 (COVID-19) in Adolescent Patients
title_full_unstemmed Severe Enteritis as the Sole Manifestation of Novel Coronavirus Disease 2019 (COVID-19) in Adolescent Patients
title_short Severe Enteritis as the Sole Manifestation of Novel Coronavirus Disease 2019 (COVID-19) in Adolescent Patients
title_sort severe enteritis as the sole manifestation of novel coronavirus disease 2019 (covid-19) in adolescent patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771253/
https://www.ncbi.nlm.nih.gov/pubmed/33425408
http://dx.doi.org/10.1155/2020/8823622
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