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Strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression

BACKGROUND: Metastatic epidural spinal cord compression (MESCC) is a debilitating sequela of cancer. Here, we evaluated various subtypes of posterior-only minimally invasive spinal (MIS) procedures utilized to address different cancers. METHODS: Within this retrospective review, we analyzed the trea...

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Autores principales: Alshareef, Mohammed Abdul, Klapthor, Gibson, Lowe, Stephen R., Barley, Jessica, Cachia, David, Frankel, Bruce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771402/
https://www.ncbi.nlm.nih.gov/pubmed/33408947
http://dx.doi.org/10.25259/SNI_815_2020
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author Alshareef, Mohammed Abdul
Klapthor, Gibson
Lowe, Stephen R.
Barley, Jessica
Cachia, David
Frankel, Bruce M.
author_facet Alshareef, Mohammed Abdul
Klapthor, Gibson
Lowe, Stephen R.
Barley, Jessica
Cachia, David
Frankel, Bruce M.
author_sort Alshareef, Mohammed Abdul
collection PubMed
description BACKGROUND: Metastatic epidural spinal cord compression (MESCC) is a debilitating sequela of cancer. Here, we evaluated various subtypes of posterior-only minimally invasive spinal (MIS) procedures utilized to address different cancers. METHODS: Within this retrospective review, we analyzed the treatment of thoracolumbar MESCC treated with three MIS techniques: decompression and fusion (Subgroup A), partial corpectomy (Subgroup B), and full corpectomy (Subgroup C). RESULTS: There were 51 patients included in the study; they averaged 58.7 years of age, and 51% were females. Most tumors were in the thoracic spine (51%). The average preoperative Frankel grade was D (62.7%); 69% (35) improved postoperatively. The patients were divided as follows: subgroup A (15 patients = 29.4%), B (19 patients = 37.3%), and C (17 patients = 33.3%). The length of hospitalization was similar (~5.4 days) for all groups. The overall complication rate was 31%, while blood loss was lower in Subgroups A and B versus C. CONCLUSION: Different MIS surgical techniques were utilized in patients with thoracic and/or lumbar MESCC. Interestingly, clinical outcomes were similar between MIS subgroups, in this study, with a trend toward higher complications and greater blood loss associated with those undergoing more aggressive MIS procedures (e.g., full corpectomy and fusion).
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spelling pubmed-77714022021-01-05 Strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression Alshareef, Mohammed Abdul Klapthor, Gibson Lowe, Stephen R. Barley, Jessica Cachia, David Frankel, Bruce M. Surg Neurol Int Original Article BACKGROUND: Metastatic epidural spinal cord compression (MESCC) is a debilitating sequela of cancer. Here, we evaluated various subtypes of posterior-only minimally invasive spinal (MIS) procedures utilized to address different cancers. METHODS: Within this retrospective review, we analyzed the treatment of thoracolumbar MESCC treated with three MIS techniques: decompression and fusion (Subgroup A), partial corpectomy (Subgroup B), and full corpectomy (Subgroup C). RESULTS: There were 51 patients included in the study; they averaged 58.7 years of age, and 51% were females. Most tumors were in the thoracic spine (51%). The average preoperative Frankel grade was D (62.7%); 69% (35) improved postoperatively. The patients were divided as follows: subgroup A (15 patients = 29.4%), B (19 patients = 37.3%), and C (17 patients = 33.3%). The length of hospitalization was similar (~5.4 days) for all groups. The overall complication rate was 31%, while blood loss was lower in Subgroups A and B versus C. CONCLUSION: Different MIS surgical techniques were utilized in patients with thoracic and/or lumbar MESCC. Interestingly, clinical outcomes were similar between MIS subgroups, in this study, with a trend toward higher complications and greater blood loss associated with those undergoing more aggressive MIS procedures (e.g., full corpectomy and fusion). Scientific Scholar 2020-12-22 /pmc/articles/PMC7771402/ /pubmed/33408947 http://dx.doi.org/10.25259/SNI_815_2020 Text en Copyright: © 2020 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Alshareef, Mohammed Abdul
Klapthor, Gibson
Lowe, Stephen R.
Barley, Jessica
Cachia, David
Frankel, Bruce M.
Strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression
title Strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression
title_full Strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression
title_fullStr Strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression
title_full_unstemmed Strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression
title_short Strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression
title_sort strategies for posterior-only minimally invasive surgery in thoracolumbar metastatic epidural spinal cord compression
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771402/
https://www.ncbi.nlm.nih.gov/pubmed/33408947
http://dx.doi.org/10.25259/SNI_815_2020
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