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Effects of Breast Cancer Adjuvant Chemotherapy Regimens on Expression of the Aging Biomarker, p16(INK4a)

BACKGROUND: Although chemotherapy saves lives, increasing evidence shows that chemotherapy accelerates aging. We previously demonstrated that mRNA expression of p16(INK4a), a biomarker of senescence and molecular aging, increased early and dramatically after beginning adjuvant anthracycline-based re...

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Detalles Bibliográficos
Autores principales:	Shachar, Shlomit S, Deal, Allison M, Reeder-Hayes, Katherine E, Nyrop, Kirsten A, Mitin, Natalia, Anders, Carey K, Carey, Lisa A, Dees, E Claire, Jolly, Trevor A, Kimmick, Gretchen G, Karuturi, Meghan S, Reinbolt, Raquel E, Speca, JoEllen C, Muss, Hyman B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771421/ https://www.ncbi.nlm.nih.gov/pubmed/33409457 http://dx.doi.org/10.1093/jncics/pkaa082

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