Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model

Most characterized angiogenic modulators are proteolytic fragments of structural plasma and/or matrix components. Herein, we have identified a novel anti-angiogenic peptide generated by the in vitro hydrolysis of the C-terminal moiety of the fibrinogen alpha chain, produced by the snake venom metall...

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Detalles Bibliográficos
Autores principales: Ferreira, Adilson Kleber, Cristofaro, Brunella, Menezes, Milene Cristina, de Oliveira, Ana Karina, Tashima, Alexandre Keiji, de Melo, Robson Lopes, Silva, Cristiane Castilho Fernandes, Rodriguez, Miryam Guillermina Palomino, Carvalho, Daniela Cajado de Oliveira Souza, de Azevedo, Ricardo Alexandre, Junior, Paulo Luiz de Sá, Mambelli, Lisley Inata, Portaro, Fernanda Vieira, Pardanaud, Luc, Eichmann, Anne, Sant’Anna, Osvaldo Augusto, Faria, Mxarcella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771711/
https://www.ncbi.nlm.nih.gov/pubmed/33473260
http://dx.doi.org/10.18632/oncotarget.27839

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