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WT1 Clone 6F-H2 Cytoplasmic Expression Differentiates Astrocytic Tumors from Astrogliosis and Associates with Tumor Grade, Histopathology, IDH1 Status, Apoptotic and Proliferative Indices: A Tissue Microarray Study

OBJECTIVES: This tissue microarray (TMA) immunohistochemical (IHC) study elucidates the role of Wilms’ tumor 1 protein (WT1) in diagnosis and prognostication of astrocytic tumors. METHODS: IHC was applied to 75 astrocytic lesions (18 astrogliosis and 57 astrocytic tumors) using antibodies directed a...

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Detalles Bibliográficos
Autores principales: Abd El Hafez, Amal, El Din Ismail Hany, Heba Salah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771928/
https://www.ncbi.nlm.nih.gov/pubmed/32856872
http://dx.doi.org/10.31557/APJCP.2020.21.8.2403