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Gene regulation gravitates toward either addition or multiplication when combining the effects of two signals
Two different cell signals often affect transcription of the same gene. In such cases, it is natural to ask how the combined transcriptional response compares to the individual responses. The most commonly used mechanistic models predict additive or multiplicative combined responses, but a systemati...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771960/ https://www.ncbi.nlm.nih.gov/pubmed/33284110 http://dx.doi.org/10.7554/eLife.59388 |