Knockdown of nrf2 Exacerbates TNF-α-Induced Proliferation and Invasion of Rheumatoid Arthritis Fibroblast-Like Synoviocytes through Activating JNK Pathway

Fibroblast-like synoviocytes (FLS) in the synovial tissue of rheumatoid arthritis (RA) exhibit over-proliferative and aggressive phenotypes, which participate in the pathophysiology of RA. In RA, little is known about the nonantioxidant effect of nuclear factor erythroid 2-related factor 2 (nrf2), t...

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Detalles Bibliográficos
Autores principales: Du, Yu, Wang, Qian, Tian, Na, Lu, Meng, Zhang, Xian-Long, Dai, Sheng-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772017/
https://www.ncbi.nlm.nih.gov/pubmed/33426091
http://dx.doi.org/10.1155/2020/6670464

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