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Non-alcoholic Fatty Liver Disease Causing Platypnea-Orthodeoxia Syndrome
Non-alcoholic fatty liver disease (NAFLD) with cryptogenic liver cirrhosis is uncommonly linked to platypnea-orthodeoxia syndrome (POS). Traditionally, this syndrome has been described in correlation to intracardiac shunting like patent foramen ovale. We report a case of a 70-year-old female, with...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772170/ https://www.ncbi.nlm.nih.gov/pubmed/33391955 http://dx.doi.org/10.7759/cureus.11727 |
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author | Ali, Hassam Shafique, Zarafshan Sehar, Alina Yalamanchili, Sreeram |
author_facet | Ali, Hassam Shafique, Zarafshan Sehar, Alina Yalamanchili, Sreeram |
author_sort | Ali, Hassam |
collection | PubMed |
description | Non-alcoholic fatty liver disease (NAFLD) with cryptogenic liver cirrhosis is uncommonly linked to platypnea-orthodeoxia syndrome (POS). Traditionally, this syndrome has been described in correlation to intracardiac shunting like patent foramen ovale. We report a case of a 70-year-old female, with a previous history of NAFLD and heart failure presenting with acute hypoxic respiratory failure secondary to fluid overload. Further investigations revealed cryptogenic presentation of POS, which was masked by her heart failure. The patient was not able to maintain her oxygen saturation levels in an upright position, with marked improvement when lying down. Her echocardiogram was significant for positive bubble study without any intracardiac shunt, hence making NAFLD as a cause of this rare presentation of POS a more likely diagnosis. |
format | Online Article Text |
id | pubmed-7772170 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-77721702020-12-31 Non-alcoholic Fatty Liver Disease Causing Platypnea-Orthodeoxia Syndrome Ali, Hassam Shafique, Zarafshan Sehar, Alina Yalamanchili, Sreeram Cureus Cardiology Non-alcoholic fatty liver disease (NAFLD) with cryptogenic liver cirrhosis is uncommonly linked to platypnea-orthodeoxia syndrome (POS). Traditionally, this syndrome has been described in correlation to intracardiac shunting like patent foramen ovale. We report a case of a 70-year-old female, with a previous history of NAFLD and heart failure presenting with acute hypoxic respiratory failure secondary to fluid overload. Further investigations revealed cryptogenic presentation of POS, which was masked by her heart failure. The patient was not able to maintain her oxygen saturation levels in an upright position, with marked improvement when lying down. Her echocardiogram was significant for positive bubble study without any intracardiac shunt, hence making NAFLD as a cause of this rare presentation of POS a more likely diagnosis. Cureus 2020-11-27 /pmc/articles/PMC7772170/ /pubmed/33391955 http://dx.doi.org/10.7759/cureus.11727 Text en Copyright © 2020, Ali et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Cardiology Ali, Hassam Shafique, Zarafshan Sehar, Alina Yalamanchili, Sreeram Non-alcoholic Fatty Liver Disease Causing Platypnea-Orthodeoxia Syndrome |
title | Non-alcoholic Fatty Liver Disease Causing Platypnea-Orthodeoxia Syndrome |
title_full | Non-alcoholic Fatty Liver Disease Causing Platypnea-Orthodeoxia Syndrome |
title_fullStr | Non-alcoholic Fatty Liver Disease Causing Platypnea-Orthodeoxia Syndrome |
title_full_unstemmed | Non-alcoholic Fatty Liver Disease Causing Platypnea-Orthodeoxia Syndrome |
title_short | Non-alcoholic Fatty Liver Disease Causing Platypnea-Orthodeoxia Syndrome |
title_sort | non-alcoholic fatty liver disease causing platypnea-orthodeoxia syndrome |
topic | Cardiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772170/ https://www.ncbi.nlm.nih.gov/pubmed/33391955 http://dx.doi.org/10.7759/cureus.11727 |
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