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Anti-CD2 Antibody-Coated Nanoparticles Containing IL-2 Induce NK Cells That Protect Lupus Mice via a TGF-β-Dependent Mechanism
We recently reported that the treatment with nanoparticles (NPs) loaded with tolerogenic cytokines suppressed the manifestations of lupus-like disease induced by the transfer of donor CD4(+) T cells from DBA/2 mice into (C57BL/6 × DBA/2)F(1) (BDF1) mice. Although the protective effects were ascribed...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772200/ https://www.ncbi.nlm.nih.gov/pubmed/33391260 http://dx.doi.org/10.3389/fimmu.2020.583338 |