Accumulation of Cerebrospinal Fluid Glycerophospholipids and Sphingolipids in Cognitively Healthy Participants With Alzheimer’s Biomarkers Precedes Lipolysis in the Dementia Stage

Insight into lipids’ roles in Alzheimer’s disease (AD) pathophysiology is limited because brain membrane lipids have not been characterized in cognitively healthy (CH) individuals. Since age is a significant risk factor of AD, we hypothesize that aging renders the amyloid precursor protein (APP) mor...

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Detalles Bibliográficos
Autores principales: Fonteh, Alfred N., Chiang, Abby J., Arakaki, Xianghong, Edminster, Sarah P., Harrington, Michael G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772205/
https://www.ncbi.nlm.nih.gov/pubmed/33390893
http://dx.doi.org/10.3389/fnins.2020.611393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772205/
https://www.ncbi.nlm.nih.gov/pubmed/33390893
http://dx.doi.org/10.3389/fnins.2020.611393

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