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Bovine Teat Cistern Microbiota Composition and Richness Are Associated With the Immune and Microbial Responses During Transition to Once-Daily Milking

The relationship between microbiota and health has been widely reported in humans and animals. We established a link between teat cistern microbiota composition and bovine mastitis, an inflammatory disease often due to bacterial infections. To further decipher the relationships between teat cistern...

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Autores principales: Rault, Lucie, Lévêque, Pierre-Alexandre, Barbey, Sarah, Launay, Frederic, Larroque, Hélène, Le Loir, Yves, Germon, Pierre, Guinard-Flament, Jocelyne, Even, Sergine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772349/
https://www.ncbi.nlm.nih.gov/pubmed/33391220
http://dx.doi.org/10.3389/fmicb.2020.602404
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author Rault, Lucie
Lévêque, Pierre-Alexandre
Barbey, Sarah
Launay, Frederic
Larroque, Hélène
Le Loir, Yves
Germon, Pierre
Guinard-Flament, Jocelyne
Even, Sergine
author_facet Rault, Lucie
Lévêque, Pierre-Alexandre
Barbey, Sarah
Launay, Frederic
Larroque, Hélène
Le Loir, Yves
Germon, Pierre
Guinard-Flament, Jocelyne
Even, Sergine
author_sort Rault, Lucie
collection PubMed
description The relationship between microbiota and health has been widely reported in humans and animals. We established a link between teat cistern microbiota composition and bovine mastitis, an inflammatory disease often due to bacterial infections. To further decipher the relationships between teat cistern microbiota and immune and microbial responses, a switch from twice- to once-daily milking (ODM) in 31 initially healthy quarters of dairy cows was used to trigger an udder perturbation. In this study, a temporal relationship was reported between initial teat cistern microbiota composition and richness, the immune response to ODM, and mastitis development. Quarters with a low initial microbiota richness and taxonomic markers such as Bacteroidetes and Proteobacteria were associated with a higher rate of mastitis during ODM. Quarters with a higher richness and taxonomic markers such as Firmicutes, including the Lachnospiraceae family, and genera such as Bifidobacterium and Corynebacterium displayed early inflammation following transition to ODM but without developing mastitis (no infection). Short-term compositional shifts of microbiota indicates that microbiotas with a higher initial richness were more strongly altered by transition to ODM, with notably the disappearance of rare OTUs. Microbiota modifications were associated with an early innate immune system stimulation, which, in turn, may have contributed to the prevention of mastitis development.
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spelling pubmed-77723492020-12-31 Bovine Teat Cistern Microbiota Composition and Richness Are Associated With the Immune and Microbial Responses During Transition to Once-Daily Milking Rault, Lucie Lévêque, Pierre-Alexandre Barbey, Sarah Launay, Frederic Larroque, Hélène Le Loir, Yves Germon, Pierre Guinard-Flament, Jocelyne Even, Sergine Front Microbiol Microbiology The relationship between microbiota and health has been widely reported in humans and animals. We established a link between teat cistern microbiota composition and bovine mastitis, an inflammatory disease often due to bacterial infections. To further decipher the relationships between teat cistern microbiota and immune and microbial responses, a switch from twice- to once-daily milking (ODM) in 31 initially healthy quarters of dairy cows was used to trigger an udder perturbation. In this study, a temporal relationship was reported between initial teat cistern microbiota composition and richness, the immune response to ODM, and mastitis development. Quarters with a low initial microbiota richness and taxonomic markers such as Bacteroidetes and Proteobacteria were associated with a higher rate of mastitis during ODM. Quarters with a higher richness and taxonomic markers such as Firmicutes, including the Lachnospiraceae family, and genera such as Bifidobacterium and Corynebacterium displayed early inflammation following transition to ODM but without developing mastitis (no infection). Short-term compositional shifts of microbiota indicates that microbiotas with a higher initial richness were more strongly altered by transition to ODM, with notably the disappearance of rare OTUs. Microbiota modifications were associated with an early innate immune system stimulation, which, in turn, may have contributed to the prevention of mastitis development. Frontiers Media S.A. 2020-12-16 /pmc/articles/PMC7772349/ /pubmed/33391220 http://dx.doi.org/10.3389/fmicb.2020.602404 Text en Copyright © 2020 Rault, Lévêque, Barbey, Launay, Larroque, Le Loir, Germon, Guinard-Flament and Even. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Microbiology
Rault, Lucie
Lévêque, Pierre-Alexandre
Barbey, Sarah
Launay, Frederic
Larroque, Hélène
Le Loir, Yves
Germon, Pierre
Guinard-Flament, Jocelyne
Even, Sergine
Bovine Teat Cistern Microbiota Composition and Richness Are Associated With the Immune and Microbial Responses During Transition to Once-Daily Milking
title Bovine Teat Cistern Microbiota Composition and Richness Are Associated With the Immune and Microbial Responses During Transition to Once-Daily Milking
title_full Bovine Teat Cistern Microbiota Composition and Richness Are Associated With the Immune and Microbial Responses During Transition to Once-Daily Milking
title_fullStr Bovine Teat Cistern Microbiota Composition and Richness Are Associated With the Immune and Microbial Responses During Transition to Once-Daily Milking
title_full_unstemmed Bovine Teat Cistern Microbiota Composition and Richness Are Associated With the Immune and Microbial Responses During Transition to Once-Daily Milking
title_short Bovine Teat Cistern Microbiota Composition and Richness Are Associated With the Immune and Microbial Responses During Transition to Once-Daily Milking
title_sort bovine teat cistern microbiota composition and richness are associated with the immune and microbial responses during transition to once-daily milking
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772349/
https://www.ncbi.nlm.nih.gov/pubmed/33391220
http://dx.doi.org/10.3389/fmicb.2020.602404
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