Cargando…

Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans

The brain requires a large amount of energy, mostly derived from the metabolism of glucose, which decreases substantially with age and neurological diseases. While mounting evidence in model organisms illustrates the central role of brain nicotinamide adenine dinucleotide (NAD) for maintaining energ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cuenoud, Bernard, Ipek, Özlem, Shevlyakova, Maya, Beaumont, Maurice, Cunnane, Stephen C., Gruetter, Rolf, Xin, Lijing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772416/ https://www.ncbi.nlm.nih.gov/pubmed/33390929 http://dx.doi.org/10.3389/fnagi.2020.609517

Ejemplares similares

Nutritional Ketosis Increases NAD(+)/NADH Ratio in Healthy Human Brain: An in Vivo Study by (31)P-MRS
por: Xin, Lijing, et al.
Publicado: (2018)

Effect of circadian rhythm on NAD and other metabolites in human brain
por: Cuenoud, Bernard, et al.
Publicado: (2023)

A combined 32‐channel receive‐loops/8‐channel transmit‐dipoles coil array for whole‐brain MR imaging at 7T
por: Clément, Jérémie, et al.
Publicado: (2019)

Phospholipide Turnover in Microsomal Membranes of the Pancreas during Enzyme Secretion
por: Redman, Colvin M., et al.
Publicado: (1959)

How Energy Metabolism Supports Cerebral Function: Insights from (13)C Magnetic Resonance Studies In vivo
por: Sonnay, Sarah, et al.
Publicado: (2017)

Evaluation of the whole auditory pathway using high-resolution and functional MRI at 7T parallel-transmit
por: Da Costa, Sandra, et al.
Publicado: (2021)

Segmenting electroencephalography wires reduces radiofrequency shielding artifacts in simultaneous electroencephalography and functional magnetic resonance imaging at 7 T
por: Lê, Thanh Phong, et al.
Publicado: (2022)

Compartmentalized Cerebral Metabolism of [1,6-(13)C]Glucose Determined by in vivo (13)C NMR Spectroscopy at 14.1 T
por: Duarte, João M. N., et al.
Publicado: (2011)

ATP and NAD(+) Deficiency in Parkinson’s Disease
por: Mischley, Laurie K., et al.
Publicado: (2023)

Metabolism of Exogenous D-Beta-Hydroxybutyrate, an Energy Substrate Avidly Consumed by the Heart and Kidney
por: Cuenoud, Bernard, et al.
Publicado: (2020)

Extracellular NAD and ATP: Partners in immune cell modulation
por: Haag, Friedrich, et al.
Publicado: (2007)

ATP11C Facilitates Phospholipid Translocation across the Plasma Membrane of All Leukocytes
por: Yabas, Mehmet, et al.
Publicado: (2016)

Electrical and optical study of nerve impulse-evoked ATP-induced, P2X-receptor-mediated sympathetic neurotransmission at single smooth muscle cells in mouse isolated vas deferens
por: Young, J.S., et al.
Publicado: (2007)

Medium Chain Triglycerides Modulate the Ketogenic Effect of a Metabolic Switch
por: Vandenberghe, Camille, et al.
Publicado: (2020)

PIRACY: An Optimized Pipeline for Functional Connectivity Analysis in the Rat Brain
por: Diao, Yujian, et al.
Publicado: (2021)

Plasma membrane phospholipid phosphatase-related proteins as pleiotropic regulators of neuron growth and excitability
por: Fuchs, Joachim, et al.
Publicado: (2022)

The phospholipid flippase ATP9A is required for the recycling pathway from the endosomes to the plasma membrane
por: Tanaka, Yoshiki, et al.
Publicado: (2016)

Antiplatelet Effect of Carbon Monoxide Is Mediated by NAD(+) and ATP Depletion
por: Kaczara, Patrycja, et al.
Publicado: (2020)

THE TURNOVER RATE OF PHOSPHOLIPIDS IN THE PLASMA OF THE DOG AS MEASURED WITH RADIOACTIVE PHOSPHORUS
por: Zilversmit, D. B., et al.
Publicado: (1943)

RELIEF FROM CONTACT INHIBITION : Early Increase in Phospholipid Turnover
por: Pasternak, C. A.
Publicado: (1972)

Systematic review of (31)P-magnetic resonance spectroscopy studies of brain high energy phosphates and membrane phospholipids in aging and Alzheimer's disease
por: Jett, Steven, et al.
Publicado: (2023)

Phospholipid synthesis inside phospholipid membrane vesicles
por: Eto, Sumie, et al.
Publicado: (2022)

Conferring the ability to utilize inorganic polyphosphate on ATP-specific NAD kinase
por: Nakamichi, Yusuke, et al.
Publicado: (2013)

A Pilot Study Investigating Changes in the Human Plasma and Urine NAD+ Metabolome During a 6 Hour Intravenous Infusion of NAD+
por: Grant, Ross, et al.
Publicado: (2019)

Dysregulated Plasma Membrane Turnover Underlying Dendritic Pathology in Neurodegenerative Diseases
por: Chung, Chang Geon, et al.
Publicado: (2020)

A ketogenic supplement improves white matter energy supply and processing speed in mild cognitive impairment
por: Roy, Maggie, et al.
Publicado: (2021)

Resonance energy transfer imaging of phospholipid vesicle interaction with a planar phospholipid membrane: undulations and attachment sites in the region of calcium-mediated membrane--membrane adhesion
Publicado: (1996)

Steady-State Brain Glucose Transport Kinetics Re-Evaluated with a Four-State Conformational Model
por: Duarte, João M. N., et al.
Publicado: (2009)

Cardiorenal ketone metabolism: a positron emission tomography study in healthy humans
por: Cuenoud, Bernard, et al.
Publicado: (2023)

Correlated Volume−Energy Fluctuations of Phospholipid Membranes: A Simulation Study
por: Pedersen, Ulf R., et al.
Publicado: (2010)

Implication of lipid turnover for the control of energy balance
por: Bernard, S., et al.
Publicado: (2023)

Refined Analysis of Brain Energy Metabolism Using In Vivo Dynamic Enrichment of (13)C Multiplets
por: Dehghani M., Masoumeh, et al.
Publicado: (2016)

Ketone-Based Metabolic Therapy: Is Increased NAD(+) a Primary Mechanism?
por: Elamin, Marwa, et al.
Publicado: (2017)

Quantifying ATP turnover in anoxic coleoptiles of rice (Oryza sativa) demonstrates preferential allocation of energy to protein synthesis
por: Edwards, Joshua M., et al.
Publicado: (2012)

Close to the Edge: Growth Restrained by the NAD(P)H/ATP Formation Flux Ratio
por: van Niel, Ed W. J., et al.
Publicado: (2017)

Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the Hippocampus
por: Duarte, João M. N., et al.
Publicado: (2019)

Metabolic signature in nucleus accumbens for anti-depressant-like effects of acetyl-L-carnitine
por: Cherix, Antoine, et al.
Publicado: (2020)

Redirection of lipid flux toward phospholipids in yeast increases fatty acid turnover and secretion
por: Ferreira, Raphael, et al.
Publicado: (2018)

Ketogenic Diet Modulates NAD(+)-Dependent Enzymes and Reduces DNA Damage in Hippocampus
por: Elamin, Marwa, et al.
Publicado: (2018)

Glutamine-to-glutamate ratio in the nucleus accumbens predicts effort-based motivated performance in humans
por: Strasser, Alina, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i6mku45tni3s2sj1416eirk5kc