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Consensus on the treatment of alopecia areata – Brazilian Society of Dermatology()()

BACKGROUND: Alopecia areata is a highly frequent disease with an impact on quality of life and several treatment options with little clinical confirmatory evidence. OBJECTIVE: To disseminate the recommendations of Brazilian dermatologists with expertise in the treatment of alopecia areata. METHODS:...

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Autores principales: Ramos, Paulo Müller, Anzai, Alessandra, Duque-Estrada, Bruna, Melo, Daniel Fernandes, Sternberg, Flavia, Santos, Leopoldo Duailibe Nogueira, Alves, Lorena Dourado, Mulinari-Brenner, Fabiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772599/
https://www.ncbi.nlm.nih.gov/pubmed/33183894
http://dx.doi.org/10.1016/j.abd.2020.05.006
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author Ramos, Paulo Müller
Anzai, Alessandra
Duque-Estrada, Bruna
Melo, Daniel Fernandes
Sternberg, Flavia
Santos, Leopoldo Duailibe Nogueira
Alves, Lorena Dourado
Mulinari-Brenner, Fabiane
author_facet Ramos, Paulo Müller
Anzai, Alessandra
Duque-Estrada, Bruna
Melo, Daniel Fernandes
Sternberg, Flavia
Santos, Leopoldo Duailibe Nogueira
Alves, Lorena Dourado
Mulinari-Brenner, Fabiane
author_sort Ramos, Paulo Müller
collection PubMed
description BACKGROUND: Alopecia areata is a highly frequent disease with an impact on quality of life and several treatment options with little clinical confirmatory evidence. OBJECTIVE: To disseminate the recommendations of Brazilian dermatologists with expertise in the treatment of alopecia areata. METHODS: Eight specialists with expertise in alopecia areata from different university centers were appointed by the Brazilian Society of Dermatology to reach a consensus on its treatment. Based on the adapted DELPHI methodology, the relevant elements were considered; then, an analysis of recent literature was carried out and the consensus was written down. Consensus on the management of alopecia areata was defined with the approval of at least 70% of the panel. RESULTS/CONCLUSIONS: Intralesional injectable corticotherapy was considered the first option for localized disease in adults. In extensive cases with signs of activity, systemic corticosteroid therapy should be considered and can be used together with immunosuppressants (corticosteroid-sparing agents). The use of an immunosensitizer (diphencyprone) is an option for stable long-term cases. Evaluation of side effects is as important as the rate of hair regrowth.
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spelling pubmed-77725992020-12-30 Consensus on the treatment of alopecia areata – Brazilian Society of Dermatology()() Ramos, Paulo Müller Anzai, Alessandra Duque-Estrada, Bruna Melo, Daniel Fernandes Sternberg, Flavia Santos, Leopoldo Duailibe Nogueira Alves, Lorena Dourado Mulinari-Brenner, Fabiane An Bras Dermatol Special Article BACKGROUND: Alopecia areata is a highly frequent disease with an impact on quality of life and several treatment options with little clinical confirmatory evidence. OBJECTIVE: To disseminate the recommendations of Brazilian dermatologists with expertise in the treatment of alopecia areata. METHODS: Eight specialists with expertise in alopecia areata from different university centers were appointed by the Brazilian Society of Dermatology to reach a consensus on its treatment. Based on the adapted DELPHI methodology, the relevant elements were considered; then, an analysis of recent literature was carried out and the consensus was written down. Consensus on the management of alopecia areata was defined with the approval of at least 70% of the panel. RESULTS/CONCLUSIONS: Intralesional injectable corticotherapy was considered the first option for localized disease in adults. In extensive cases with signs of activity, systemic corticosteroid therapy should be considered and can be used together with immunosuppressants (corticosteroid-sparing agents). The use of an immunosensitizer (diphencyprone) is an option for stable long-term cases. Evaluation of side effects is as important as the rate of hair regrowth. Sociedade Brasileira de Dermatologia 2020 2020-10-08 /pmc/articles/PMC7772599/ /pubmed/33183894 http://dx.doi.org/10.1016/j.abd.2020.05.006 Text en © 2020 Sociedade Brasileira de Dermatologia. Published by Elsevier España, S.L.U. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Special Article
Ramos, Paulo Müller
Anzai, Alessandra
Duque-Estrada, Bruna
Melo, Daniel Fernandes
Sternberg, Flavia
Santos, Leopoldo Duailibe Nogueira
Alves, Lorena Dourado
Mulinari-Brenner, Fabiane
Consensus on the treatment of alopecia areata – Brazilian Society of Dermatology()()
title Consensus on the treatment of alopecia areata – Brazilian Society of Dermatology()()
title_full Consensus on the treatment of alopecia areata – Brazilian Society of Dermatology()()
title_fullStr Consensus on the treatment of alopecia areata – Brazilian Society of Dermatology()()
title_full_unstemmed Consensus on the treatment of alopecia areata – Brazilian Society of Dermatology()()
title_short Consensus on the treatment of alopecia areata – Brazilian Society of Dermatology()()
title_sort consensus on the treatment of alopecia areata – brazilian society of dermatology()()
topic Special Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772599/
https://www.ncbi.nlm.nih.gov/pubmed/33183894
http://dx.doi.org/10.1016/j.abd.2020.05.006
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