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Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing potentially fatal coronavirus disease-19 (COVID-19), with a significant health and economic burden around the globe. Currently many clinical studies are undergoing but still there is no any specific approved therapy or dr...

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Detalles Bibliográficos
Autores principales: Nile, Shivraj Hariram, Kai, Guoyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772620/
https://www.ncbi.nlm.nih.gov/pubmed/33390627
http://dx.doi.org/10.1007/s12088-020-00919-x
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author Nile, Shivraj Hariram
Kai, Guoyin
author_facet Nile, Shivraj Hariram
Kai, Guoyin
author_sort Nile, Shivraj Hariram
collection PubMed
description The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing potentially fatal coronavirus disease-19 (COVID-19), with a significant health and economic burden around the globe. Currently many clinical studies are undergoing but still there is no any specific approved therapy or drug established for effective treatment of COVID-19. This review aimed to analyses various clinical studies which have been registered in www.clinicaltrials.gov and http://www.chictr.org.cn were registered with natural plant-based medicines and Traditional Chinese medicine (TCM) for discovering effective treatment and prevention of COVID-19. Total 46 and 64 natural drug and TCM interventions were identified which mainly determined the preventive strategies and possible treatments for COVID-19 infection. We identified that most of the clinical trial undergoing on natural compound like heparin and vitamin C as therapeutic agents and immune boosters for against COVID-19. Traditional Chinese medicines and herbal medicines can be effectively used as a preventive therapy against COVID-19 and after successful clinical trials and these potential therapies can be promoted by countries around the world. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at (10.1007/s12088-020-00919-x).
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spelling pubmed-77726202020-12-30 Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19 Nile, Shivraj Hariram Kai, Guoyin Indian J Microbiol Review Article The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing potentially fatal coronavirus disease-19 (COVID-19), with a significant health and economic burden around the globe. Currently many clinical studies are undergoing but still there is no any specific approved therapy or drug established for effective treatment of COVID-19. This review aimed to analyses various clinical studies which have been registered in www.clinicaltrials.gov and http://www.chictr.org.cn were registered with natural plant-based medicines and Traditional Chinese medicine (TCM) for discovering effective treatment and prevention of COVID-19. Total 46 and 64 natural drug and TCM interventions were identified which mainly determined the preventive strategies and possible treatments for COVID-19 infection. We identified that most of the clinical trial undergoing on natural compound like heparin and vitamin C as therapeutic agents and immune boosters for against COVID-19. Traditional Chinese medicines and herbal medicines can be effectively used as a preventive therapy against COVID-19 and after successful clinical trials and these potential therapies can be promoted by countries around the world. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at (10.1007/s12088-020-00919-x). Springer India 2020-12-30 2021-03 /pmc/articles/PMC7772620/ /pubmed/33390627 http://dx.doi.org/10.1007/s12088-020-00919-x Text en © Association of Microbiologists of India 2020
spellingShingle Review Article
Nile, Shivraj Hariram
Kai, Guoyin
Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19
title Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19
title_full Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19
title_fullStr Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19
title_full_unstemmed Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19
title_short Recent Clinical Trials on Natural Products and Traditional Chinese Medicine Combating the COVID-19
title_sort recent clinical trials on natural products and traditional chinese medicine combating the covid-19
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772620/
https://www.ncbi.nlm.nih.gov/pubmed/33390627
http://dx.doi.org/10.1007/s12088-020-00919-x
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