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Pivotal role of long non-coding ribonucleic acid-X-inactive specific transcript in regulating immune checkpoint programmed death ligand 1 through a shared pathway between miR-194-5p and miR-155-5p in hepatocellular carcinoma

BACKGROUND: Anti-programmed death therapy has thrust immunotherapy into the spotlight. However, such therapy has a modest response in hepatocellular carcinoma (HCC). Epigenetic immunomodulation is a suggestive combinatorial therapy with immune checkpoint blockade. Non-coding ribonucleic acid (ncRNA)...

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Detalles Bibliográficos
Autores principales: Atwa, Sara M, Handoussa, Heba, Hosny, Karim M, Odenthal, Margarete, El Tayebi, Hend M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772730/
https://www.ncbi.nlm.nih.gov/pubmed/33442449
http://dx.doi.org/10.4254/wjh.v12.i12.1211

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