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The RNA-binding profile of the splicing factor SRSF6 in immortalized human pancreatic β-cells

In pancreatic β-cells, the expression of the splicing factor SRSF6 is regulated by GLIS3, a transcription factor encoded by a diabetes susceptibility gene. SRSF6 down-regulation promotes β-cell demise through splicing dysregulation of central genes for β-cells function and survival, but how RNAs are...

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Detalles Bibliográficos
Autores principales:	Alvelos, Maria Inês, Brüggemann, Mirko, Sutandy, FX Reymond, Juan-Mateu, Jonàs, Colli, Maikel Luis, Busch, Anke, Lopes, Miguel, Castela, Ângela, Aartsma-Rus, Annemieke, König, Julian, Zarnack, Kathi, Eizirik, Décio L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772782/ https://www.ncbi.nlm.nih.gov/pubmed/33376132 http://dx.doi.org/10.26508/lsa.202000825

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