Oxysterols present in Alzheimer's disease brain induce synaptotoxicity by activating astrocytes: A major role for lipocalin-2

Among Alzheimer's disease (AD) brain hallmarks, the presence of reactive astrocytes was demonstrated to correlate with neuronal loss and cognitive deficits. Evidence indeed supports the role of reactive astrocytes as mediators of changes in neurons, including synapses. However, the complexity a...

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Detalles Bibliográficos
Autores principales: Staurenghi, Erica, Cerrato, Valentina, Gamba, Paola, Testa, Gabriella, Giannelli, Serena, Leoni, Valerio, Caccia, Claudio, Buffo, Annalisa, Noble, Wendy, Perez-Nievas, Beatriz Gomez, Leonarduzzi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772793/
https://www.ncbi.nlm.nih.gov/pubmed/33360775
http://dx.doi.org/10.1016/j.redox.2020.101837

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