Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade

Inflammation can support or restrain cancer progression and the response to therapy. Here, we searched for primary regulators of cancer-inhibitory inflammation through deep profiling of inflammatory tumor microenvironments (TMEs) linked to immune-dependent control in mice. We found that early intrat...

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Detalles Bibliográficos
Autores principales: Bonavita, Eduardo, Bromley, Christian P., Jonsson, Gustav, Pelly, Victoria S., Sahoo, Sudhakar, Walwyn-Brown, Katherine, Mensurado, Sofia, Moeini, Agrin, Flanagan, Eimear, Bell, Charlotte R., Chiang, Shih-Chieh, Chikkanna-Gowda, C.P., Rogers, Neil, Silva-Santos, Bruno, Jaillon, Sebastien, Mantovani, Alberto, Reis e Sousa, Caetano, Guerra, Nadia, Davis, Daniel M., Zelenay, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772804/
https://www.ncbi.nlm.nih.gov/pubmed/33220234
http://dx.doi.org/10.1016/j.immuni.2020.10.020

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