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Integrating biokinetics and in vitro studies to evaluate developmental neurotoxicity induced by chlorpyrifos in human iPSC-derived neural stem cells undergoing differentiation towards neuronal and glial cells

For some complex toxicological endpoints, chemical safety assessment has conventionally relied on animal testing. Apart from the ethical issues, also scientific considerations have been raised concerning the traditional approach, highlighting the importance for considering real life exposure scenari...

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Detalles Bibliográficos
Autores principales:	Di Consiglio, Emma, Pistollato, Francesca, Mendoza-De Gyves, Emilio, Bal-Price, Anna, Testai, Emanuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pergamon In Cooperation With The Reproductive Toxicology Center 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772889/ https://www.ncbi.nlm.nih.gov/pubmed/33011216 http://dx.doi.org/10.1016/j.reprotox.2020.09.010

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