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Semi-supervised learning for somatic variant calling and peptide identification in personalized cancer immunotherapy

BACKGROUND: Personalized cancer vaccines are emerging as one of the most promising approaches to immunotherapy of advanced cancers. However, only a small proportion of the neoepitopes generated by somatic DNA mutations in cancer cells lead to tumor rejection. Since it is impractical to experimentall...

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Detalles Bibliográficos
Autores principales:	Sherafat, Elham, Force, Jordan, Măndoiu, Ion I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7772914/ https://www.ncbi.nlm.nih.gov/pubmed/33375939 http://dx.doi.org/10.1186/s12859-020-03813-x

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