DACH1 mutation frequency in endometrial cancer is associated with high tumor mutation burden

OBJECTIVE: DACH1 is a transcriptional repressor and tumor suppressor gene frequently mutated in melanoma, bladder, and prostate cancer. Loss of DACH1 expression is associated with poor prognostic features and reduced overall survival in uterine cancer. In this study, we utilized the Oncology Researc...

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Detalles Bibliográficos
Autores principales: Riggs, McKayla J., Lin, Nan, Wang, Chi, Piecoro, Dava W., Miller, Rachel W., Hampton, Oliver A., Rao, Mahadev, Ueland, Frederick R., Kolesar, Jill M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773279/
https://www.ncbi.nlm.nih.gov/pubmed/33378353
http://dx.doi.org/10.1371/journal.pone.0244558

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