Cargando…

Optimal surveillance mitigation of COVID'19 disease outbreak: Fractional order optimal control of compartment model

In present time, the whole world is in the phase of war against the deadly pandemic COVID'19 and working on different interventions in this regard. Variety of strategies are taken into account from ground level to the state to reduce the transmission rate. For this purpose, the epidemiologists...

Descripción completa

Detalles Bibliográficos
Autores principales: Razzaq, Oyoon Abdul, Rehman, Daniyal Ur, Khan, Najeeb Alam, Ahmadian, Ali, Ferrara, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773320/
https://www.ncbi.nlm.nih.gov/pubmed/33398241
http://dx.doi.org/10.1016/j.rinp.2020.103715
_version_ 1783630036907065344
author Razzaq, Oyoon Abdul
Rehman, Daniyal Ur
Khan, Najeeb Alam
Ahmadian, Ali
Ferrara, Massimiliano
author_facet Razzaq, Oyoon Abdul
Rehman, Daniyal Ur
Khan, Najeeb Alam
Ahmadian, Ali
Ferrara, Massimiliano
author_sort Razzaq, Oyoon Abdul
collection PubMed
description In present time, the whole world is in the phase of war against the deadly pandemic COVID'19 and working on different interventions in this regard. Variety of strategies are taken into account from ground level to the state to reduce the transmission rate. For this purpose, the epidemiologists are also augmenting their contribution in structuring such models that could depict a scheme to diminish the basic reproduction number. These tactics also include the awareness campaigns initiated by the stakeholders through digital, print media and etc. Analyzing the cost and profit effectiveness of these tactics, we design an optimal control dynamical model to study the proficiency of each strategy in reducing the virulence of COVID'19. The aim is to illustrate the memory effect on the dynamics of COVID'19 with and without prevention measures through fractional calculus. Therefore, the structure of the model is in line with generalized proportional fractional derivative to assess the effects at each chronological change. Awareness about using medical mask, social distancing, frequent use of sanitizer or cleaning hand and supportive care during treatment are the strategies followed worldwide in this fight. Taking these into consideration, the optimal objective function proposed for the surveillance mitigation of COVID'19, is contemplated as the cost function. The effect analysis is supported through graphs and tabulated values. In addition, sensitivity inspection of basic reproduction number is also carried out with respect to different values of fractional index and cost function. Ultimately, social distancing and supportive care of infected are found to be significant in decreasing the basic reproduction number more rapidly.
format Online
Article
Text
id pubmed-7773320
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Authors. Published by Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-77733202020-12-31 Optimal surveillance mitigation of COVID'19 disease outbreak: Fractional order optimal control of compartment model Razzaq, Oyoon Abdul Rehman, Daniyal Ur Khan, Najeeb Alam Ahmadian, Ali Ferrara, Massimiliano Results Phys Article In present time, the whole world is in the phase of war against the deadly pandemic COVID'19 and working on different interventions in this regard. Variety of strategies are taken into account from ground level to the state to reduce the transmission rate. For this purpose, the epidemiologists are also augmenting their contribution in structuring such models that could depict a scheme to diminish the basic reproduction number. These tactics also include the awareness campaigns initiated by the stakeholders through digital, print media and etc. Analyzing the cost and profit effectiveness of these tactics, we design an optimal control dynamical model to study the proficiency of each strategy in reducing the virulence of COVID'19. The aim is to illustrate the memory effect on the dynamics of COVID'19 with and without prevention measures through fractional calculus. Therefore, the structure of the model is in line with generalized proportional fractional derivative to assess the effects at each chronological change. Awareness about using medical mask, social distancing, frequent use of sanitizer or cleaning hand and supportive care during treatment are the strategies followed worldwide in this fight. Taking these into consideration, the optimal objective function proposed for the surveillance mitigation of COVID'19, is contemplated as the cost function. The effect analysis is supported through graphs and tabulated values. In addition, sensitivity inspection of basic reproduction number is also carried out with respect to different values of fractional index and cost function. Ultimately, social distancing and supportive care of infected are found to be significant in decreasing the basic reproduction number more rapidly. The Authors. Published by Elsevier B.V. 2021-01 2020-12-30 /pmc/articles/PMC7773320/ /pubmed/33398241 http://dx.doi.org/10.1016/j.rinp.2020.103715 Text en © 2020 The Authors. Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Razzaq, Oyoon Abdul
Rehman, Daniyal Ur
Khan, Najeeb Alam
Ahmadian, Ali
Ferrara, Massimiliano
Optimal surveillance mitigation of COVID'19 disease outbreak: Fractional order optimal control of compartment model
title Optimal surveillance mitigation of COVID'19 disease outbreak: Fractional order optimal control of compartment model
title_full Optimal surveillance mitigation of COVID'19 disease outbreak: Fractional order optimal control of compartment model
title_fullStr Optimal surveillance mitigation of COVID'19 disease outbreak: Fractional order optimal control of compartment model
title_full_unstemmed Optimal surveillance mitigation of COVID'19 disease outbreak: Fractional order optimal control of compartment model
title_short Optimal surveillance mitigation of COVID'19 disease outbreak: Fractional order optimal control of compartment model
title_sort optimal surveillance mitigation of covid'19 disease outbreak: fractional order optimal control of compartment model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773320/
https://www.ncbi.nlm.nih.gov/pubmed/33398241
http://dx.doi.org/10.1016/j.rinp.2020.103715
work_keys_str_mv AT razzaqoyoonabdul optimalsurveillancemitigationofcovid19diseaseoutbreakfractionalorderoptimalcontrolofcompartmentmodel
AT rehmandaniyalur optimalsurveillancemitigationofcovid19diseaseoutbreakfractionalorderoptimalcontrolofcompartmentmodel
AT khannajeebalam optimalsurveillancemitigationofcovid19diseaseoutbreakfractionalorderoptimalcontrolofcompartmentmodel
AT ahmadianali optimalsurveillancemitigationofcovid19diseaseoutbreakfractionalorderoptimalcontrolofcompartmentmodel
AT ferraramassimiliano optimalsurveillancemitigationofcovid19diseaseoutbreakfractionalorderoptimalcontrolofcompartmentmodel