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chTOG is a conserved mitotic error correction factor

Accurate chromosome segregation requires kinetochores on duplicated chromatids to biorient by attaching to dynamic microtubules from opposite spindle poles, which exerts forces to bring kinetochores under tension. However, kinetochores initially bind to microtubules indiscriminately, resulting in er...

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Detalles Bibliográficos
Autores principales: Herman, Jacob A, Miller, Matthew P, Biggins, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773332/
https://www.ncbi.nlm.nih.gov/pubmed/33377866
http://dx.doi.org/10.7554/eLife.61773