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NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression

Osteocytes, the most abundant bone cell type, are derived from osteoblasts through a process in which they are embedded in an osteoid. We previously showed that nutrient restriction promotes the osteocyte transcriptional program and is associated with increased mitochondrial biogenesis. Here, we sho...

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Detalles Bibliográficos
Autores principales: Sánchez-de-Diego, Cristina, Pedrazza, Leonardo, Pimenta-Lopes, Carolina, Martinez-Martinez, Arturo, Dahdah, Norma, Valer, José Antonio, Garcia-Roves, Pablo, Rosa, Jose Luis, Ventura, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773566/
https://www.ncbi.nlm.nih.gov/pubmed/33373776
http://dx.doi.org/10.1016/j.redox.2020.101845