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NRF2 function in osteocytes is required for bone homeostasis and drives osteocytic gene expression
Osteocytes, the most abundant bone cell type, are derived from osteoblasts through a process in which they are embedded in an osteoid. We previously showed that nutrient restriction promotes the osteocyte transcriptional program and is associated with increased mitochondrial biogenesis. Here, we sho...
Autores principales: | Sánchez-de-Diego, Cristina, Pedrazza, Leonardo, Pimenta-Lopes, Carolina, Martinez-Martinez, Arturo, Dahdah, Norma, Valer, José Antonio, Garcia-Roves, Pablo, Rosa, Jose Luis, Ventura, Francesc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773566/ https://www.ncbi.nlm.nih.gov/pubmed/33373776 http://dx.doi.org/10.1016/j.redox.2020.101845 |
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