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Serine 165 phosphorylation of SHARPIN regulates the activation of NF-κB

The adaptor SHARPIN composes, together with the E3 ligases HOIP and HOIL1, the linear ubiquitin chain assembly complex (LUBAC). This enzymatic complex catalyzes and stamps atypical linear ubiquitin chains onto substrates to modify their fate and has been linked to the regulation of the NF-κB pathway...

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Detalles Bibliográficos
Autores principales:	Thys, An, Trillet, Kilian, Rosińska, Sara, Gayraud, Audrey, Douanne, Tiphaine, Danger, Yannic, Renaud, Clotilde C.N., Antigny, Luc, Lavigne, Régis, Pineau, Charles, Com, Emmanuelle, Vérité, Franck, Gavard, Julie, Bidère, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773595/ https://www.ncbi.nlm.nih.gov/pubmed/33392484 http://dx.doi.org/10.1016/j.isci.2020.101939

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