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The case for an HIV cure and how to get there
In light of the increasing global burden of new HIV infections, growing financial requirements, and shifting funding landscape, the global health community must accelerate the development and delivery of an HIV cure to complement existing prevention modalities. An effective curative intervention cou...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773626/ https://www.ncbi.nlm.nih.gov/pubmed/33271124 http://dx.doi.org/10.1016/S2352-3018(20)30232-0 |
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author | Dybul, Mark Attoye, Timothy Baptiste, Solange Cherutich, Peter Dabis, François Deeks, Steven G Dieffenbach, Carl Doehle, Brian Goodenow, Maureen M Jiang, Adam Kemps, Dominic Lewin, Sharon R Lumpkin, Murray M Mathae, Lauren McCune, Joseph M Ndung'u, Thumbi Nsubuga, Moses Peay, Holly L Pottage, John Warren, Mitchell Sikazwe, Izukanji |
author_facet | Dybul, Mark Attoye, Timothy Baptiste, Solange Cherutich, Peter Dabis, François Deeks, Steven G Dieffenbach, Carl Doehle, Brian Goodenow, Maureen M Jiang, Adam Kemps, Dominic Lewin, Sharon R Lumpkin, Murray M Mathae, Lauren McCune, Joseph M Ndung'u, Thumbi Nsubuga, Moses Peay, Holly L Pottage, John Warren, Mitchell Sikazwe, Izukanji |
author_sort | Dybul, Mark |
collection | PubMed |
description | In light of the increasing global burden of new HIV infections, growing financial requirements, and shifting funding landscape, the global health community must accelerate the development and delivery of an HIV cure to complement existing prevention modalities. An effective curative intervention could prevent new infections, overcome the limitations of antiretroviral treatment, combat stigma and discrimination, and provide a sustainable financial solution for pandemic control. We propose steps to plan for an HIV cure now, including defining a target product profile and establishing the HIV Cure Africa Acceleration Partnership (HCAAP), a multidisciplinary public-private partnership that will catalyse and promote HIV cure research through diverse stakeholder engagement. HCAAP will convene stakeholders, including people living with HIV, at an early stage to accelerate the design, social acceptability, and rapid adoption of HIV-cure products. |
format | Online Article Text |
id | pubmed-7773626 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier B.V |
record_format | MEDLINE/PubMed |
spelling | pubmed-77736262021-01-05 The case for an HIV cure and how to get there Dybul, Mark Attoye, Timothy Baptiste, Solange Cherutich, Peter Dabis, François Deeks, Steven G Dieffenbach, Carl Doehle, Brian Goodenow, Maureen M Jiang, Adam Kemps, Dominic Lewin, Sharon R Lumpkin, Murray M Mathae, Lauren McCune, Joseph M Ndung'u, Thumbi Nsubuga, Moses Peay, Holly L Pottage, John Warren, Mitchell Sikazwe, Izukanji Lancet HIV Viewpoint In light of the increasing global burden of new HIV infections, growing financial requirements, and shifting funding landscape, the global health community must accelerate the development and delivery of an HIV cure to complement existing prevention modalities. An effective curative intervention could prevent new infections, overcome the limitations of antiretroviral treatment, combat stigma and discrimination, and provide a sustainable financial solution for pandemic control. We propose steps to plan for an HIV cure now, including defining a target product profile and establishing the HIV Cure Africa Acceleration Partnership (HCAAP), a multidisciplinary public-private partnership that will catalyse and promote HIV cure research through diverse stakeholder engagement. HCAAP will convene stakeholders, including people living with HIV, at an early stage to accelerate the design, social acceptability, and rapid adoption of HIV-cure products. Elsevier B.V 2020-11-30 /pmc/articles/PMC7773626/ /pubmed/33271124 http://dx.doi.org/10.1016/S2352-3018(20)30232-0 Text en © 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Viewpoint Dybul, Mark Attoye, Timothy Baptiste, Solange Cherutich, Peter Dabis, François Deeks, Steven G Dieffenbach, Carl Doehle, Brian Goodenow, Maureen M Jiang, Adam Kemps, Dominic Lewin, Sharon R Lumpkin, Murray M Mathae, Lauren McCune, Joseph M Ndung'u, Thumbi Nsubuga, Moses Peay, Holly L Pottage, John Warren, Mitchell Sikazwe, Izukanji The case for an HIV cure and how to get there |
title | The case for an HIV cure and how to get there |
title_full | The case for an HIV cure and how to get there |
title_fullStr | The case for an HIV cure and how to get there |
title_full_unstemmed | The case for an HIV cure and how to get there |
title_short | The case for an HIV cure and how to get there |
title_sort | case for an hiv cure and how to get there |
topic | Viewpoint |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773626/ https://www.ncbi.nlm.nih.gov/pubmed/33271124 http://dx.doi.org/10.1016/S2352-3018(20)30232-0 |
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