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The case for an HIV cure and how to get there

In light of the increasing global burden of new HIV infections, growing financial requirements, and shifting funding landscape, the global health community must accelerate the development and delivery of an HIV cure to complement existing prevention modalities. An effective curative intervention cou...

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Autores principales: Dybul, Mark, Attoye, Timothy, Baptiste, Solange, Cherutich, Peter, Dabis, François, Deeks, Steven G, Dieffenbach, Carl, Doehle, Brian, Goodenow, Maureen M, Jiang, Adam, Kemps, Dominic, Lewin, Sharon R, Lumpkin, Murray M, Mathae, Lauren, McCune, Joseph M, Ndung'u, Thumbi, Nsubuga, Moses, Peay, Holly L, Pottage, John, Warren, Mitchell, Sikazwe, Izukanji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773626/
https://www.ncbi.nlm.nih.gov/pubmed/33271124
http://dx.doi.org/10.1016/S2352-3018(20)30232-0
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author Dybul, Mark
Attoye, Timothy
Baptiste, Solange
Cherutich, Peter
Dabis, François
Deeks, Steven G
Dieffenbach, Carl
Doehle, Brian
Goodenow, Maureen M
Jiang, Adam
Kemps, Dominic
Lewin, Sharon R
Lumpkin, Murray M
Mathae, Lauren
McCune, Joseph M
Ndung'u, Thumbi
Nsubuga, Moses
Peay, Holly L
Pottage, John
Warren, Mitchell
Sikazwe, Izukanji
author_facet Dybul, Mark
Attoye, Timothy
Baptiste, Solange
Cherutich, Peter
Dabis, François
Deeks, Steven G
Dieffenbach, Carl
Doehle, Brian
Goodenow, Maureen M
Jiang, Adam
Kemps, Dominic
Lewin, Sharon R
Lumpkin, Murray M
Mathae, Lauren
McCune, Joseph M
Ndung'u, Thumbi
Nsubuga, Moses
Peay, Holly L
Pottage, John
Warren, Mitchell
Sikazwe, Izukanji
author_sort Dybul, Mark
collection PubMed
description In light of the increasing global burden of new HIV infections, growing financial requirements, and shifting funding landscape, the global health community must accelerate the development and delivery of an HIV cure to complement existing prevention modalities. An effective curative intervention could prevent new infections, overcome the limitations of antiretroviral treatment, combat stigma and discrimination, and provide a sustainable financial solution for pandemic control. We propose steps to plan for an HIV cure now, including defining a target product profile and establishing the HIV Cure Africa Acceleration Partnership (HCAAP), a multidisciplinary public-private partnership that will catalyse and promote HIV cure research through diverse stakeholder engagement. HCAAP will convene stakeholders, including people living with HIV, at an early stage to accelerate the design, social acceptability, and rapid adoption of HIV-cure products.
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spelling pubmed-77736262021-01-05 The case for an HIV cure and how to get there Dybul, Mark Attoye, Timothy Baptiste, Solange Cherutich, Peter Dabis, François Deeks, Steven G Dieffenbach, Carl Doehle, Brian Goodenow, Maureen M Jiang, Adam Kemps, Dominic Lewin, Sharon R Lumpkin, Murray M Mathae, Lauren McCune, Joseph M Ndung'u, Thumbi Nsubuga, Moses Peay, Holly L Pottage, John Warren, Mitchell Sikazwe, Izukanji Lancet HIV Viewpoint In light of the increasing global burden of new HIV infections, growing financial requirements, and shifting funding landscape, the global health community must accelerate the development and delivery of an HIV cure to complement existing prevention modalities. An effective curative intervention could prevent new infections, overcome the limitations of antiretroviral treatment, combat stigma and discrimination, and provide a sustainable financial solution for pandemic control. We propose steps to plan for an HIV cure now, including defining a target product profile and establishing the HIV Cure Africa Acceleration Partnership (HCAAP), a multidisciplinary public-private partnership that will catalyse and promote HIV cure research through diverse stakeholder engagement. HCAAP will convene stakeholders, including people living with HIV, at an early stage to accelerate the design, social acceptability, and rapid adoption of HIV-cure products. Elsevier B.V 2020-11-30 /pmc/articles/PMC7773626/ /pubmed/33271124 http://dx.doi.org/10.1016/S2352-3018(20)30232-0 Text en © 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Viewpoint
Dybul, Mark
Attoye, Timothy
Baptiste, Solange
Cherutich, Peter
Dabis, François
Deeks, Steven G
Dieffenbach, Carl
Doehle, Brian
Goodenow, Maureen M
Jiang, Adam
Kemps, Dominic
Lewin, Sharon R
Lumpkin, Murray M
Mathae, Lauren
McCune, Joseph M
Ndung'u, Thumbi
Nsubuga, Moses
Peay, Holly L
Pottage, John
Warren, Mitchell
Sikazwe, Izukanji
The case for an HIV cure and how to get there
title The case for an HIV cure and how to get there
title_full The case for an HIV cure and how to get there
title_fullStr The case for an HIV cure and how to get there
title_full_unstemmed The case for an HIV cure and how to get there
title_short The case for an HIV cure and how to get there
title_sort case for an hiv cure and how to get there
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773626/
https://www.ncbi.nlm.nih.gov/pubmed/33271124
http://dx.doi.org/10.1016/S2352-3018(20)30232-0
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