Cargando…
Targeting the Malaria Parasite cGMP-Dependent Protein Kinase to Develop New Drugs
The single-celled apicomplexan parasite Plasmodium falciparum is responsible for the majority of deaths due to malaria each year. The selection of drug resistance has been a recurring theme over the decades with each new drug that is developed. It is therefore crucial that future generations of drug...
Autores principales: | Baker, David A., Matralis, Alexios N., Osborne, Simon A., Large, Jonathan M., Penzo, Maria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773720/ https://www.ncbi.nlm.nih.gov/pubmed/33391223 http://dx.doi.org/10.3389/fmicb.2020.602803 |
Ejemplares similares
-
Gametogenesis in Malaria Parasites Is Mediated by the cGMP-Dependent Protein Kinase
por: McRobert, Louisa, et al.
Publicado: (2008) -
The role of the cGMP-dependent protein kinase in development of the malaria parasite
por: McRobert, Louisa, et al.
Publicado: (2009) -
Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress
por: Collins, Christine R., et al.
Publicado: (2013) -
Plasmodium falciparum cGMP-Dependent Protein Kinase – A Novel Chemotherapeutic Target
por: Rotella, David, et al.
Publicado: (2021) -
Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation
por: El Bakkouri, Majida, et al.
Publicado: (2019)