Nuclear-Encoded lncRNA MALAT1 Epigenetically Controls Metabolic Reprogramming in HCC Cells through the Mitophagy Pathway

Mitochondrial dysfunction is a metabolic hallmark of cancer cells. In search of molecular factors involved in this dysregulation in hepatocellular carcinoma (HCC), we found that the nuclear-encoded long noncoding RNA (lncRNA) MALAT1 (metastasis-associated lung adenocarcinoma transcript 1) was aberra...

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Detalles Bibliográficos
Autores principales: Zhao, Yijing, Zhou, Lei, Li, Hui, Sun, Tingge, Wen, Xue, Li, Xueli, Meng, Ying, Li, Yan, Liu, Mengmeng, Liu, Shanshan, Kim, Su-Jeong, Xiao, Jialin, Li, Lingyu, Zhang, Songling, Li, Wei, Cohen, Pinchas, Hoffman, Andrew R., Hu, Ji-Fan, Cui, Jiuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773746/
https://www.ncbi.nlm.nih.gov/pubmed/33425485
http://dx.doi.org/10.1016/j.omtn.2020.09.040

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