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Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue

The clinical presentation of dengue virus (DENV) infection is variable. Severe complications mainly result from exacerbated immune responses. Type I interferons (IFN-I) are important in antiviral responses and form a crucial link between innate and adaptive immunity. Their contribution to host defen...

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Detalles Bibliográficos
Autores principales:	Upasani, Vinit, Scagnolari, Carolina, Frasca, Federica, Smith, Nikaïa, Bondet, Vincent, Vanderlinden, Axelle, Lay, Sokchea, Auerswald, Heidi, Heng, Sothy, Laurent, Denis, Ly, Sowath, Duong, Veasna, Antonelli, Guido, Dussart, Philippe, Duffy, Darragh, Cantaert, Tineke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773824/ https://www.ncbi.nlm.nih.gov/pubmed/33391269 http://dx.doi.org/10.3389/fimmu.2020.605087

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