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Tubeimoside I Inhibits Cell Proliferation and Induces a Partly Disrupted and Cytoprotective Autophagy Through Rapidly Hyperactivation of MEK1/2-ERK1/2 Cascade via Promoting PTP1B in Melanoma
Tubeimoside I (TBMS1), also referred to as tubeimoside A, is a natural compound extracted from the plant Tu Bei Mu (Bolbostemma paniculatum), which is a traditional Chinese herb used to treat multiple diseases for more than 1,000 years. Studies in recent years reported its anti-tumor activity in sev...
Autores principales: | Du, Juan, Dong, Zhen, Tan, Li, Tan, Mengqin, Zhang, Fang, Zhang, Kui, Pan, Guangzhao, Li, Chongyang, Shi, Shaomin, Zhang, Yanli, Liu, Yaling, Cui, Hongjuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773826/ https://www.ncbi.nlm.nih.gov/pubmed/33392197 http://dx.doi.org/10.3389/fcell.2020.607757 |
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