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The Natural Compound Oblongifolin C Exhibits Anticancer Activity by Inhibiting HSPA8 and Cathepsin B In Vitro

PPAPs (Polycyclic polyprenylated acylphloroglucinols) are a class of compounds with diverse bioactivities, including anticancer effects. Oblongifolin C (OC) is a PPAP isolated from the plant of Garcinia yunnanensis Hu. We previously discovered that OC induces apoptosis, inhibits autophagic flux, and...

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Detalles Bibliográficos
Autores principales: Han, Li, Xu, Danqing, Xi, Zhichao, Wu, Man, Nik Nabil, Wan Najbah, Zhang, Juan, Sui, Hua, Fu, Wenwei, Zhou, Hua, Lao, Yuanzhi, Xu, Gang, Guo, Cheng, Xu, Hongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773843/
https://www.ncbi.nlm.nih.gov/pubmed/33390942
http://dx.doi.org/10.3389/fphar.2020.564833