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Using magnetoencephalography to examine word recognition, lateralization, and future language skills in 14-month-old infants

Word learning is a significant milestone in language acquisition. The second year of life marks a period of dramatic advances in infants’ expressive and receptive word-processing abilities. Studies show that in adulthood, language processing is left-hemisphere dominant. However, adults learning a se...

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Autores principales: Bosseler, Alexis N., Clarke, Maggie, Tavabi, Kambiz, Larson, Eric D., Hippe, Daniel S., Taulu, Samu, Kuhl, Patricia K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773883/
https://www.ncbi.nlm.nih.gov/pubmed/33360832
http://dx.doi.org/10.1016/j.dcn.2020.100901
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author Bosseler, Alexis N.
Clarke, Maggie
Tavabi, Kambiz
Larson, Eric D.
Hippe, Daniel S.
Taulu, Samu
Kuhl, Patricia K.
author_facet Bosseler, Alexis N.
Clarke, Maggie
Tavabi, Kambiz
Larson, Eric D.
Hippe, Daniel S.
Taulu, Samu
Kuhl, Patricia K.
author_sort Bosseler, Alexis N.
collection PubMed
description Word learning is a significant milestone in language acquisition. The second year of life marks a period of dramatic advances in infants’ expressive and receptive word-processing abilities. Studies show that in adulthood, language processing is left-hemisphere dominant. However, adults learning a second language activate right-hemisphere brain functions. In infancy, acquisition of a first language involves recruitment of bilateral brain networks, and strong left-hemisphere dominance emerges by the third year. In the current study we focus on 14-month-old infants in the earliest stages of word learning using infant magnetoencephalography (MEG) brain imagining to characterize neural activity in response to familiar and unfamiliar words. Specifically, we examine the relationship between right-hemisphere brain responses and prospective measures of vocabulary growth. As expected, MEG source modeling revealed a broadly distributed network in frontal, temporal and parietal cortex that distinguished word classes between 150–900 ms after word onset. Importantly, brain activity in the right frontal cortex in response to familiar words was highly correlated with vocabulary growth at 18, 21, 24, and 27 months. Specifically, higher activation to familiar words in the 150–300 ms interval was associated with faster vocabulary growth, reflecting processing efficiency, whereas higher activation to familiar words in the 600–900 ms interval was associated with slower vocabulary growth, reflecting cognitive effort. These findings inform research and theory on the involvement of right frontal cortex in specific cognitive processes and individual differences related to attention that may play an important role in the development of left-lateralized word processing.
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spelling pubmed-77738832021-01-05 Using magnetoencephalography to examine word recognition, lateralization, and future language skills in 14-month-old infants Bosseler, Alexis N. Clarke, Maggie Tavabi, Kambiz Larson, Eric D. Hippe, Daniel S. Taulu, Samu Kuhl, Patricia K. Dev Cogn Neurosci Original Research Word learning is a significant milestone in language acquisition. The second year of life marks a period of dramatic advances in infants’ expressive and receptive word-processing abilities. Studies show that in adulthood, language processing is left-hemisphere dominant. However, adults learning a second language activate right-hemisphere brain functions. In infancy, acquisition of a first language involves recruitment of bilateral brain networks, and strong left-hemisphere dominance emerges by the third year. In the current study we focus on 14-month-old infants in the earliest stages of word learning using infant magnetoencephalography (MEG) brain imagining to characterize neural activity in response to familiar and unfamiliar words. Specifically, we examine the relationship between right-hemisphere brain responses and prospective measures of vocabulary growth. As expected, MEG source modeling revealed a broadly distributed network in frontal, temporal and parietal cortex that distinguished word classes between 150–900 ms after word onset. Importantly, brain activity in the right frontal cortex in response to familiar words was highly correlated with vocabulary growth at 18, 21, 24, and 27 months. Specifically, higher activation to familiar words in the 150–300 ms interval was associated with faster vocabulary growth, reflecting processing efficiency, whereas higher activation to familiar words in the 600–900 ms interval was associated with slower vocabulary growth, reflecting cognitive effort. These findings inform research and theory on the involvement of right frontal cortex in specific cognitive processes and individual differences related to attention that may play an important role in the development of left-lateralized word processing. Elsevier 2020-12-17 /pmc/articles/PMC7773883/ /pubmed/33360832 http://dx.doi.org/10.1016/j.dcn.2020.100901 Text en © 2020 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Original Research
Bosseler, Alexis N.
Clarke, Maggie
Tavabi, Kambiz
Larson, Eric D.
Hippe, Daniel S.
Taulu, Samu
Kuhl, Patricia K.
Using magnetoencephalography to examine word recognition, lateralization, and future language skills in 14-month-old infants
title Using magnetoencephalography to examine word recognition, lateralization, and future language skills in 14-month-old infants
title_full Using magnetoencephalography to examine word recognition, lateralization, and future language skills in 14-month-old infants
title_fullStr Using magnetoencephalography to examine word recognition, lateralization, and future language skills in 14-month-old infants
title_full_unstemmed Using magnetoencephalography to examine word recognition, lateralization, and future language skills in 14-month-old infants
title_short Using magnetoencephalography to examine word recognition, lateralization, and future language skills in 14-month-old infants
title_sort using magnetoencephalography to examine word recognition, lateralization, and future language skills in 14-month-old infants
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773883/
https://www.ncbi.nlm.nih.gov/pubmed/33360832
http://dx.doi.org/10.1016/j.dcn.2020.100901
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