Cargando…
Restoring Balance to the Outer Membrane: YejM’s Role in LPS Regulation
Gram-negative bacteria produce an asymmetric outer membrane (OM) that is particularly impermeant to many antibiotics and characterized by lipopolysaccharide (LPS) exclusively at the cell surface. LPS biogenesis remains an ideal target for therapeutic intervention, as disruption could kill bacteria o...
Autores principales: | Simpson, Brent W., Douglass, Martin V., Trent, M. Stephen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7773988/ https://www.ncbi.nlm.nih.gov/pubmed/33323515 http://dx.doi.org/10.1128/mBio.02624-20 |
Ejemplares similares
-
The essential inner membrane protein YejM is a metalloenzyme
por: Gabale, Uma, et al.
Publicado: (2020) -
Salmonella enterica Serovar Typhimurium Uses PbgA/YejM To Regulate Lipopolysaccharide Assembly during Bacteremia
por: Cian, Melina B., et al.
Publicado: (2019) -
Crystallization and preliminary X-ray diffraction analysis of YejM from
Salmonella typhimurium: an essential inner membrane protein involved in outer membrane directed cardiolipin transport
por: Gabale, Uma, et al.
Publicado: (2017) -
YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide
por: Guest, Randi L., et al.
Publicado: (2020) -
Regulation of the First Committed Step in Lipopolysaccharide Biosynthesis Catalyzed by LpxC Requires the Essential Protein LapC (YejM) and HslVU Protease
por: Biernacka, Daria, et al.
Publicado: (2020)