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Implementation of early management of iron deficiency in pregnancy during the SARS-CoV-2 pandemic

Iron deficiency is the commonest cause for anaemia worldwide making it a formidable issue particularly during pregnancy because of increased iron demands. This study looked at establishing a lower limit of normal for haemoglobin concentration (Hb) in our population and to proactively address potenti...

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Autores principales: Stewart, T., Lambourne, J., Thorp-Jones, D., Thomas, D.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774011/
https://www.ncbi.nlm.nih.gov/pubmed/33418463
http://dx.doi.org/10.1016/j.ejogrb.2020.12.055
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author Stewart, T.
Lambourne, J.
Thorp-Jones, D.
Thomas, D.W.
author_facet Stewart, T.
Lambourne, J.
Thorp-Jones, D.
Thomas, D.W.
author_sort Stewart, T.
collection PubMed
description Iron deficiency is the commonest cause for anaemia worldwide making it a formidable issue particularly during pregnancy because of increased iron demands. This study looked at establishing a lower limit of normal for haemoglobin concentration (Hb) in our population and to proactively address potentially symptomatic iron deficiency during the current SARS-CoV-2 pandemic. The lower limit of normal for Hb in our 1715 first trimester pregnancy cohort was 116 g/L. This is in contrast with guidance suggesting Hb levels down to 110 g/L are normal. In addition there was evidence of limited testing performed to look for iron deficiency with only 18 % having a serum ferritin checked. Most anaemia was normocytic suggesting that microcytosis is only a late marker of iron deficiency lacking sensitivity. A strategy to avoid hospital contact during the COVID-19 pandemic is proposed.
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spelling pubmed-77740112020-12-31 Implementation of early management of iron deficiency in pregnancy during the SARS-CoV-2 pandemic Stewart, T. Lambourne, J. Thorp-Jones, D. Thomas, D.W. Eur J Obstet Gynecol Reprod Biol Review Article Iron deficiency is the commonest cause for anaemia worldwide making it a formidable issue particularly during pregnancy because of increased iron demands. This study looked at establishing a lower limit of normal for haemoglobin concentration (Hb) in our population and to proactively address potentially symptomatic iron deficiency during the current SARS-CoV-2 pandemic. The lower limit of normal for Hb in our 1715 first trimester pregnancy cohort was 116 g/L. This is in contrast with guidance suggesting Hb levels down to 110 g/L are normal. In addition there was evidence of limited testing performed to look for iron deficiency with only 18 % having a serum ferritin checked. Most anaemia was normocytic suggesting that microcytosis is only a late marker of iron deficiency lacking sensitivity. A strategy to avoid hospital contact during the COVID-19 pandemic is proposed. Published by Elsevier B.V. 2021-03 2020-12-31 /pmc/articles/PMC7774011/ /pubmed/33418463 http://dx.doi.org/10.1016/j.ejogrb.2020.12.055 Text en © 2020 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review Article
Stewart, T.
Lambourne, J.
Thorp-Jones, D.
Thomas, D.W.
Implementation of early management of iron deficiency in pregnancy during the SARS-CoV-2 pandemic
title Implementation of early management of iron deficiency in pregnancy during the SARS-CoV-2 pandemic
title_full Implementation of early management of iron deficiency in pregnancy during the SARS-CoV-2 pandemic
title_fullStr Implementation of early management of iron deficiency in pregnancy during the SARS-CoV-2 pandemic
title_full_unstemmed Implementation of early management of iron deficiency in pregnancy during the SARS-CoV-2 pandemic
title_short Implementation of early management of iron deficiency in pregnancy during the SARS-CoV-2 pandemic
title_sort implementation of early management of iron deficiency in pregnancy during the sars-cov-2 pandemic
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774011/
https://www.ncbi.nlm.nih.gov/pubmed/33418463
http://dx.doi.org/10.1016/j.ejogrb.2020.12.055
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