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Contribution of Uptake and Efflux Transporters to Oral Pharmacokinetics of Furosemide

[Image: see text] Furosemide is a widely used diuretic for treating excessive fluid accumulation caused by disease conditions like heart failure and liver cirrhosis. Furosemide tablet formulation exhibits variable pharmacokinetics (PK) with bioavailability ranging from 10 to almost 100%. To explain...

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Detalles Bibliográficos
Autores principales: Chapa, Revathi, Li, Cindy Yanfei, Basit, Abdul, Thakur, Aarzoo, Ladumor, Mayur K, Sharma, Sheena, Singh, Saranjit, Selen, Arzu, Prasad, Bhagwat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774078/
https://www.ncbi.nlm.nih.gov/pubmed/33403255
http://dx.doi.org/10.1021/acsomega.0c03930