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Contribution of Uptake and Efflux Transporters to Oral Pharmacokinetics of Furosemide
[Image: see text] Furosemide is a widely used diuretic for treating excessive fluid accumulation caused by disease conditions like heart failure and liver cirrhosis. Furosemide tablet formulation exhibits variable pharmacokinetics (PK) with bioavailability ranging from 10 to almost 100%. To explain...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774078/ https://www.ncbi.nlm.nih.gov/pubmed/33403255 http://dx.doi.org/10.1021/acsomega.0c03930 |