Cargando…

Combined medical and surgical management for cicatricial ectropion in lamellar ichthyosis: A report of three cases

Ichthyosis is a rare inherited skin disorder characterized by abnormal keratinization of the epidermis. Cicatricial ectropion is the most common ophthalmic feature of congenital ichthyosis. Progressive subepithelial cicatrization and abnormal cornification of eyelid skin cause progressive ectropion...

Descripción completa

Detalles Bibliográficos
Autores principales: Subramanian, Nirmala, Nivean, Pratheeba Devi, Alam, Md Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774180/
https://www.ncbi.nlm.nih.gov/pubmed/33120713
http://dx.doi.org/10.4103/ijo.IJO_855_20
_version_ 1783630210398158848
author Subramanian, Nirmala
Nivean, Pratheeba Devi
Alam, Md Shahid
author_facet Subramanian, Nirmala
Nivean, Pratheeba Devi
Alam, Md Shahid
author_sort Subramanian, Nirmala
collection PubMed
description Ichthyosis is a rare inherited skin disorder characterized by abnormal keratinization of the epidermis. Cicatricial ectropion is the most common ophthalmic feature of congenital ichthyosis. Progressive subepithelial cicatrization and abnormal cornification of eyelid skin cause progressive ectropion in both eyelids, leading to lagophthalmos and corneal exposure. Surgical correction of cicatricial ectropion in these cases is challenging with unsatisfactory results. Proper processing of the donor and recipient site with lubricants and topical retinoids before surgery makes grafting easier and its survival better. We present three cases of lamellar ichthyosis with cicatricial ectropion managed with combined preoperative topical therapy followed by surgery. All patients had extremely good surgical outcomes, with none of them requiring repeat surgery.
format Online
Article
Text
id pubmed-7774180
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-77741802021-01-07 Combined medical and surgical management for cicatricial ectropion in lamellar ichthyosis: A report of three cases Subramanian, Nirmala Nivean, Pratheeba Devi Alam, Md Shahid Indian J Ophthalmol Case Reports Ichthyosis is a rare inherited skin disorder characterized by abnormal keratinization of the epidermis. Cicatricial ectropion is the most common ophthalmic feature of congenital ichthyosis. Progressive subepithelial cicatrization and abnormal cornification of eyelid skin cause progressive ectropion in both eyelids, leading to lagophthalmos and corneal exposure. Surgical correction of cicatricial ectropion in these cases is challenging with unsatisfactory results. Proper processing of the donor and recipient site with lubricants and topical retinoids before surgery makes grafting easier and its survival better. We present three cases of lamellar ichthyosis with cicatricial ectropion managed with combined preoperative topical therapy followed by surgery. All patients had extremely good surgical outcomes, with none of them requiring repeat surgery. Wolters Kluwer - Medknow 2020-11 2020-10-26 /pmc/articles/PMC7774180/ /pubmed/33120713 http://dx.doi.org/10.4103/ijo.IJO_855_20 Text en Copyright: © 2020 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Subramanian, Nirmala
Nivean, Pratheeba Devi
Alam, Md Shahid
Combined medical and surgical management for cicatricial ectropion in lamellar ichthyosis: A report of three cases
title Combined medical and surgical management for cicatricial ectropion in lamellar ichthyosis: A report of three cases
title_full Combined medical and surgical management for cicatricial ectropion in lamellar ichthyosis: A report of three cases
title_fullStr Combined medical and surgical management for cicatricial ectropion in lamellar ichthyosis: A report of three cases
title_full_unstemmed Combined medical and surgical management for cicatricial ectropion in lamellar ichthyosis: A report of three cases
title_short Combined medical and surgical management for cicatricial ectropion in lamellar ichthyosis: A report of three cases
title_sort combined medical and surgical management for cicatricial ectropion in lamellar ichthyosis: a report of three cases
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774180/
https://www.ncbi.nlm.nih.gov/pubmed/33120713
http://dx.doi.org/10.4103/ijo.IJO_855_20
work_keys_str_mv AT subramaniannirmala combinedmedicalandsurgicalmanagementforcicatricialectropioninlamellarichthyosisareportofthreecases
AT niveanpratheebadevi combinedmedicalandsurgicalmanagementforcicatricialectropioninlamellarichthyosisareportofthreecases
AT alammdshahid combinedmedicalandsurgicalmanagementforcicatricialectropioninlamellarichthyosisareportofthreecases