Role of secukinumab in ankylosing spondylitis with tubercular uveitis

We present the case of a 32-year-old Indian male one-eyed individual with a history of unilateral panuveitis with HLA B 27 positive spondyloarthropathy on systemic immunosuppressant (Adalimumab). He developed recurrent inflammation in the same eye in a span of 2 years, later complicated with retinal...

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Autores principales: Mahendradas, Padmamalini, Jain, Vikramraj K, Thomas, Sherina, Kawali, Ankush, Sanjay, Srinivasan, Shetty, Bhujang K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774187/
https://www.ncbi.nlm.nih.gov/pubmed/33120695
http://dx.doi.org/10.4103/ijo.IJO_1081_20
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author Mahendradas, Padmamalini
Jain, Vikramraj K
Thomas, Sherina
Kawali, Ankush
Sanjay, Srinivasan
Shetty, Bhujang K
author_facet Mahendradas, Padmamalini
Jain, Vikramraj K
Thomas, Sherina
Kawali, Ankush
Sanjay, Srinivasan
Shetty, Bhujang K
author_sort Mahendradas, Padmamalini
collection PubMed
description We present the case of a 32-year-old Indian male one-eyed individual with a history of unilateral panuveitis with HLA B 27 positive spondyloarthropathy on systemic immunosuppressant (Adalimumab). He developed recurrent inflammation in the same eye in a span of 2 years, later complicated with retinal vasculitis. On evaluation, he was diagnosed with tubercular uveitis and started on antitubercular treatment along with systemic steroids. Inview of Increased IOP due to steroid response, Inj. Secukinumab ( IL 17 A inhibitor) was started and significant improvement was noted.
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spelling pubmed-77741872021-01-07 Role of secukinumab in ankylosing spondylitis with tubercular uveitis Mahendradas, Padmamalini Jain, Vikramraj K Thomas, Sherina Kawali, Ankush Sanjay, Srinivasan Shetty, Bhujang K Indian J Ophthalmol Case Reports We present the case of a 32-year-old Indian male one-eyed individual with a history of unilateral panuveitis with HLA B 27 positive spondyloarthropathy on systemic immunosuppressant (Adalimumab). He developed recurrent inflammation in the same eye in a span of 2 years, later complicated with retinal vasculitis. On evaluation, he was diagnosed with tubercular uveitis and started on antitubercular treatment along with systemic steroids. Inview of Increased IOP due to steroid response, Inj. Secukinumab ( IL 17 A inhibitor) was started and significant improvement was noted. Wolters Kluwer - Medknow 2020-11 2020-10-26 /pmc/articles/PMC7774187/ /pubmed/33120695 http://dx.doi.org/10.4103/ijo.IJO_1081_20 Text en Copyright: © 2020 Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Reports
Mahendradas, Padmamalini
Jain, Vikramraj K
Thomas, Sherina
Kawali, Ankush
Sanjay, Srinivasan
Shetty, Bhujang K
Role of secukinumab in ankylosing spondylitis with tubercular uveitis
title Role of secukinumab in ankylosing spondylitis with tubercular uveitis
title_full Role of secukinumab in ankylosing spondylitis with tubercular uveitis
title_fullStr Role of secukinumab in ankylosing spondylitis with tubercular uveitis
title_full_unstemmed Role of secukinumab in ankylosing spondylitis with tubercular uveitis
title_short Role of secukinumab in ankylosing spondylitis with tubercular uveitis
title_sort role of secukinumab in ankylosing spondylitis with tubercular uveitis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774187/
https://www.ncbi.nlm.nih.gov/pubmed/33120695
http://dx.doi.org/10.4103/ijo.IJO_1081_20
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