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Trauma severity associated with stress index in emergency settings: an observational prediction‐and‐validation study

AIM: Early judgments for treating severe trauma patients are essential for life‐saving. Stress index (SI), obtained from a division of blood glucose level by serum potassium at arrival, might be useful for early prediction. However, the efficacy of SI was unknown. The purpose of this study was to id...

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Autores principales: Taniguchi, Hayato, Doi, Tomoki, Abe, Takeru, Takeuchi, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774291/
https://www.ncbi.nlm.nih.gov/pubmed/33391764
http://dx.doi.org/10.1002/ams2.493
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author Taniguchi, Hayato
Doi, Tomoki
Abe, Takeru
Takeuchi, Ichiro
author_facet Taniguchi, Hayato
Doi, Tomoki
Abe, Takeru
Takeuchi, Ichiro
author_sort Taniguchi, Hayato
collection PubMed
description AIM: Early judgments for treating severe trauma patients are essential for life‐saving. Stress index (SI), obtained from a division of blood glucose level by serum potassium at arrival, might be useful for early prediction. However, the efficacy of SI was unknown. The purpose of this study was to identify and validate prediction models of severe trauma (ST) and the need for damage control operation (DCOP) and massive transfusion (MT) by using SI among trauma patients. METHODS: This study was a retrospective and prospective observational study. The prediction models were created by 1‐year retrospective data of 167 trauma patients. The prediction models were validated by 6 months of prospective data of 87 trauma patients. RESULTS: The prediction model for ST contained respiratory rate and SI as significant factors. The prediction model for DCOP contained SI. The prediction model for MT contained systolic blood pressure and SI. The correlation of probability of MT, ST, and DCOP was r = 0.70 (P < 0.001), r = 0.46 (P < 0.001), and r = 0.15 (P = 0.196), respectively. The predicted probability of MT, ST, and DCOP showed 0.93 (95% confidence interval [CI], 0.88–0.90) and 0.80 (95% CI, 0.74–0.86), and 0.79 (95% CI, 0.70–0.88). CONCLUSION: We identified and validated our prediction models for ST and the need for DCOP and MT among trauma patients using SI as a main predictor. Our models indicated that fewer variables in an early phase of the treatment process can inform clinicians regarding how severe a patient is and which intervention is needed.
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spelling pubmed-77742912020-12-31 Trauma severity associated with stress index in emergency settings: an observational prediction‐and‐validation study Taniguchi, Hayato Doi, Tomoki Abe, Takeru Takeuchi, Ichiro Acute Med Surg Original Articles AIM: Early judgments for treating severe trauma patients are essential for life‐saving. Stress index (SI), obtained from a division of blood glucose level by serum potassium at arrival, might be useful for early prediction. However, the efficacy of SI was unknown. The purpose of this study was to identify and validate prediction models of severe trauma (ST) and the need for damage control operation (DCOP) and massive transfusion (MT) by using SI among trauma patients. METHODS: This study was a retrospective and prospective observational study. The prediction models were created by 1‐year retrospective data of 167 trauma patients. The prediction models were validated by 6 months of prospective data of 87 trauma patients. RESULTS: The prediction model for ST contained respiratory rate and SI as significant factors. The prediction model for DCOP contained SI. The prediction model for MT contained systolic blood pressure and SI. The correlation of probability of MT, ST, and DCOP was r = 0.70 (P < 0.001), r = 0.46 (P < 0.001), and r = 0.15 (P = 0.196), respectively. The predicted probability of MT, ST, and DCOP showed 0.93 (95% confidence interval [CI], 0.88–0.90) and 0.80 (95% CI, 0.74–0.86), and 0.79 (95% CI, 0.70–0.88). CONCLUSION: We identified and validated our prediction models for ST and the need for DCOP and MT among trauma patients using SI as a main predictor. Our models indicated that fewer variables in an early phase of the treatment process can inform clinicians regarding how severe a patient is and which intervention is needed. John Wiley and Sons Inc. 2020-03-04 /pmc/articles/PMC7774291/ /pubmed/33391764 http://dx.doi.org/10.1002/ams2.493 Text en © 2020 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Taniguchi, Hayato
Doi, Tomoki
Abe, Takeru
Takeuchi, Ichiro
Trauma severity associated with stress index in emergency settings: an observational prediction‐and‐validation study
title Trauma severity associated with stress index in emergency settings: an observational prediction‐and‐validation study
title_full Trauma severity associated with stress index in emergency settings: an observational prediction‐and‐validation study
title_fullStr Trauma severity associated with stress index in emergency settings: an observational prediction‐and‐validation study
title_full_unstemmed Trauma severity associated with stress index in emergency settings: an observational prediction‐and‐validation study
title_short Trauma severity associated with stress index in emergency settings: an observational prediction‐and‐validation study
title_sort trauma severity associated with stress index in emergency settings: an observational prediction‐and‐validation study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774291/
https://www.ncbi.nlm.nih.gov/pubmed/33391764
http://dx.doi.org/10.1002/ams2.493
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