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A simple correction for COVID-19 sampling bias
COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not reflect the true underlying populations. For instance, indivi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774323/ https://www.ncbi.nlm.nih.gov/pubmed/33385402 http://dx.doi.org/10.1016/j.jtbi.2020.110556 |
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author | Díaz-Pachón, Daniel Andrés Rao, J. Sunil |
author_facet | Díaz-Pachón, Daniel Andrés Rao, J. Sunil |
author_sort | Díaz-Pachón, Daniel Andrés |
collection | PubMed |
description | COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not reflect the true underlying populations. For instance, individuals with strong symptoms are more likely to be tested than those with no symptoms. This results in biased estimates of prevalence (too high). Typical post-sampling corrections are not always possible. Here we present a simple bias correction methodology derived and adapted from a correction for publication bias in meta analysis studies. The methodology is general enough to allow a wide variety of customization making it more useful in practice. Implementation is easily done using already collected information. Via a simulation and two real datasets, we show that the bias corrections can provide dramatic reductions in estimation error. |
format | Online Article Text |
id | pubmed-7774323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77743232020-12-31 A simple correction for COVID-19 sampling bias Díaz-Pachón, Daniel Andrés Rao, J. Sunil J Theor Biol Article COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not reflect the true underlying populations. For instance, individuals with strong symptoms are more likely to be tested than those with no symptoms. This results in biased estimates of prevalence (too high). Typical post-sampling corrections are not always possible. Here we present a simple bias correction methodology derived and adapted from a correction for publication bias in meta analysis studies. The methodology is general enough to allow a wide variety of customization making it more useful in practice. Implementation is easily done using already collected information. Via a simulation and two real datasets, we show that the bias corrections can provide dramatic reductions in estimation error. Elsevier Ltd. 2021-03-07 2020-12-30 /pmc/articles/PMC7774323/ /pubmed/33385402 http://dx.doi.org/10.1016/j.jtbi.2020.110556 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Díaz-Pachón, Daniel Andrés Rao, J. Sunil A simple correction for COVID-19 sampling bias |
title | A simple correction for COVID-19 sampling bias |
title_full | A simple correction for COVID-19 sampling bias |
title_fullStr | A simple correction for COVID-19 sampling bias |
title_full_unstemmed | A simple correction for COVID-19 sampling bias |
title_short | A simple correction for COVID-19 sampling bias |
title_sort | simple correction for covid-19 sampling bias |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774323/ https://www.ncbi.nlm.nih.gov/pubmed/33385402 http://dx.doi.org/10.1016/j.jtbi.2020.110556 |
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