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A simple correction for COVID-19 sampling bias

COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not reflect the true underlying populations. For instance, indivi...

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Detalles Bibliográficos
Autores principales: Díaz-Pachón, Daniel Andrés, Rao, J. Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774323/
https://www.ncbi.nlm.nih.gov/pubmed/33385402
http://dx.doi.org/10.1016/j.jtbi.2020.110556
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author Díaz-Pachón, Daniel Andrés
Rao, J. Sunil
author_facet Díaz-Pachón, Daniel Andrés
Rao, J. Sunil
author_sort Díaz-Pachón, Daniel Andrés
collection PubMed
description COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not reflect the true underlying populations. For instance, individuals with strong symptoms are more likely to be tested than those with no symptoms. This results in biased estimates of prevalence (too high). Typical post-sampling corrections are not always possible. Here we present a simple bias correction methodology derived and adapted from a correction for publication bias in meta analysis studies. The methodology is general enough to allow a wide variety of customization making it more useful in practice. Implementation is easily done using already collected information. Via a simulation and two real datasets, we show that the bias corrections can provide dramatic reductions in estimation error.
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spelling pubmed-77743232020-12-31 A simple correction for COVID-19 sampling bias Díaz-Pachón, Daniel Andrés Rao, J. Sunil J Theor Biol Article COVID-19 testing has become a standard approach for estimating prevalence which then assist in public health decision making to contain and mitigate the spread of the disease. The sampling designs used are often biased in that they do not reflect the true underlying populations. For instance, individuals with strong symptoms are more likely to be tested than those with no symptoms. This results in biased estimates of prevalence (too high). Typical post-sampling corrections are not always possible. Here we present a simple bias correction methodology derived and adapted from a correction for publication bias in meta analysis studies. The methodology is general enough to allow a wide variety of customization making it more useful in practice. Implementation is easily done using already collected information. Via a simulation and two real datasets, we show that the bias corrections can provide dramatic reductions in estimation error. Elsevier Ltd. 2021-03-07 2020-12-30 /pmc/articles/PMC7774323/ /pubmed/33385402 http://dx.doi.org/10.1016/j.jtbi.2020.110556 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Díaz-Pachón, Daniel Andrés
Rao, J. Sunil
A simple correction for COVID-19 sampling bias
title A simple correction for COVID-19 sampling bias
title_full A simple correction for COVID-19 sampling bias
title_fullStr A simple correction for COVID-19 sampling bias
title_full_unstemmed A simple correction for COVID-19 sampling bias
title_short A simple correction for COVID-19 sampling bias
title_sort simple correction for covid-19 sampling bias
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774323/
https://www.ncbi.nlm.nih.gov/pubmed/33385402
http://dx.doi.org/10.1016/j.jtbi.2020.110556
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