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Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin
We used commercially available ELISAs to test 68 samples from coronavirus disease cases and prepandemic controls from Benin. We noted <25% false-positive results among controls, likely due to unspecific immune responses elicited by acute malaria. Serologic tests must be carefully evaluated to ass...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Centers for Disease Control and Prevention
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774555/ https://www.ncbi.nlm.nih.gov/pubmed/33261717 http://dx.doi.org/10.3201/eid2701.203281 |
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| author | Yadouleton, Anges Sander, Anna-Lena Moreira-Soto, Andres Tchibozo, Carine Hounkanrin, Gildas Badou, Yvette Fischer, Carlo Krause, Nina Akogbeto, Petas de Oliveira Filho, Edmilson F. Dossou, Anges Brünink, Sebastian Aïssi, Melchior A. Joël Djingarey, Mamoudou Harouna Hounkpatin, Benjamin Nagel, Michael Drexler, Jan Felix |
| author_facet | Yadouleton, Anges Sander, Anna-Lena Moreira-Soto, Andres Tchibozo, Carine Hounkanrin, Gildas Badou, Yvette Fischer, Carlo Krause, Nina Akogbeto, Petas de Oliveira Filho, Edmilson F. Dossou, Anges Brünink, Sebastian Aïssi, Melchior A. Joël Djingarey, Mamoudou Harouna Hounkpatin, Benjamin Nagel, Michael Drexler, Jan Felix |
| author_sort | Yadouleton, Anges |
| collection | PubMed |
| description | We used commercially available ELISAs to test 68 samples from coronavirus disease cases and prepandemic controls from Benin. We noted <25% false-positive results among controls, likely due to unspecific immune responses elicited by acute malaria. Serologic tests must be carefully evaluated to assess coronavirus disease spread and immunity in tropical regions. |
| format | Online Article Text |
| id | pubmed-7774555 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | Centers for Disease Control and Prevention |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-77745552021-01-01 Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin Yadouleton, Anges Sander, Anna-Lena Moreira-Soto, Andres Tchibozo, Carine Hounkanrin, Gildas Badou, Yvette Fischer, Carlo Krause, Nina Akogbeto, Petas de Oliveira Filho, Edmilson F. Dossou, Anges Brünink, Sebastian Aïssi, Melchior A. Joël Djingarey, Mamoudou Harouna Hounkpatin, Benjamin Nagel, Michael Drexler, Jan Felix Emerg Infect Dis Dispatch We used commercially available ELISAs to test 68 samples from coronavirus disease cases and prepandemic controls from Benin. We noted <25% false-positive results among controls, likely due to unspecific immune responses elicited by acute malaria. Serologic tests must be carefully evaluated to assess coronavirus disease spread and immunity in tropical regions. Centers for Disease Control and Prevention 2021-01 /pmc/articles/PMC7774555/ /pubmed/33261717 http://dx.doi.org/10.3201/eid2701.203281 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
| spellingShingle | Dispatch Yadouleton, Anges Sander, Anna-Lena Moreira-Soto, Andres Tchibozo, Carine Hounkanrin, Gildas Badou, Yvette Fischer, Carlo Krause, Nina Akogbeto, Petas de Oliveira Filho, Edmilson F. Dossou, Anges Brünink, Sebastian Aïssi, Melchior A. Joël Djingarey, Mamoudou Harouna Hounkpatin, Benjamin Nagel, Michael Drexler, Jan Felix Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin |
| title | Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin |
| title_full | Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin |
| title_fullStr | Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin |
| title_full_unstemmed | Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin |
| title_short | Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin |
| title_sort | limited specificity of serologic tests for sars-cov-2 antibody detection, benin |
| topic | Dispatch |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774555/ https://www.ncbi.nlm.nih.gov/pubmed/33261717 http://dx.doi.org/10.3201/eid2701.203281 |
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