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Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa

Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained...

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Detalles Bibliográficos
Autores principales: Heinrich, Fabian, Meißner, Kira, Langenwalder, Felicia, Püschel, Klaus, Nörz, Dominik, Hoffmann, Armin, Lütgehetmann, Marc, Aepfelbacher, Martin, Bibiza-Freiwald, Eric, Pfefferle, Susanne, Heinemann, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774572/
https://www.ncbi.nlm.nih.gov/pubmed/33327991
http://dx.doi.org/10.3201/eid2701.203112
Descripción
Sumario:Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained infectivity is supported by virus isolation up to 35 hours postmortem.