Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa

Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained...

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Detalles Bibliográficos
Autores principales: Heinrich, Fabian, Meißner, Kira, Langenwalder, Felicia, Püschel, Klaus, Nörz, Dominik, Hoffmann, Armin, Lütgehetmann, Marc, Aepfelbacher, Martin, Bibiza-Freiwald, Eric, Pfefferle, Susanne, Heinemann, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774572/
https://www.ncbi.nlm.nih.gov/pubmed/33327991
http://dx.doi.org/10.3201/eid2701.203112
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author Heinrich, Fabian
Meißner, Kira
Langenwalder, Felicia
Püschel, Klaus
Nörz, Dominik
Hoffmann, Armin
Lütgehetmann, Marc
Aepfelbacher, Martin
Bibiza-Freiwald, Eric
Pfefferle, Susanne
Heinemann, Axel
author_facet Heinrich, Fabian
Meißner, Kira
Langenwalder, Felicia
Püschel, Klaus
Nörz, Dominik
Hoffmann, Armin
Lütgehetmann, Marc
Aepfelbacher, Martin
Bibiza-Freiwald, Eric
Pfefferle, Susanne
Heinemann, Axel
author_sort Heinrich, Fabian
collection PubMed
description Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained infectivity is supported by virus isolation up to 35 hours postmortem.
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spelling pubmed-77745722021-01-01 Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa Heinrich, Fabian Meißner, Kira Langenwalder, Felicia Püschel, Klaus Nörz, Dominik Hoffmann, Armin Lütgehetmann, Marc Aepfelbacher, Martin Bibiza-Freiwald, Eric Pfefferle, Susanne Heinemann, Axel Emerg Infect Dis Research Letter Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained infectivity is supported by virus isolation up to 35 hours postmortem. Centers for Disease Control and Prevention 2021-01 /pmc/articles/PMC7774572/ /pubmed/33327991 http://dx.doi.org/10.3201/eid2701.203112 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Heinrich, Fabian
Meißner, Kira
Langenwalder, Felicia
Püschel, Klaus
Nörz, Dominik
Hoffmann, Armin
Lütgehetmann, Marc
Aepfelbacher, Martin
Bibiza-Freiwald, Eric
Pfefferle, Susanne
Heinemann, Axel
Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa
title Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa
title_full Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa
title_fullStr Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa
title_full_unstemmed Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa
title_short Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa
title_sort postmortem stability of sars-cov-2 in nasopharyngeal mucosa
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774572/
https://www.ncbi.nlm.nih.gov/pubmed/33327991
http://dx.doi.org/10.3201/eid2701.203112
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