Novel 6-Month Treatment for Drug-Resistant Tuberculosis, United States

The US Food and Drug Administration approved a 6-month regimen of pretomanid, bedaquiline, and linezolid for extensively drug-resistant or multidrug-intolerant tuberculosis after a trial in South Africa demonstrated 90% effectiveness 6 months posttreatment. We report on a patient who completed the r...

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Autores principales: Haley, Connie A., Macias, Patricia, Jasuja, Supriya, Jones, Betsy A., Rowlinson, Marie-Claire, Jaimon, Roshni, Onderko, Pennelyn, Darnall, Elaine, Gomez, Maria E., Peloquin, Charles, Ashkin, David, Goswami, Neela D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774582/
https://www.ncbi.nlm.nih.gov/pubmed/33227229
http://dx.doi.org/10.3201/eid2701.203766
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author Haley, Connie A.
Macias, Patricia
Jasuja, Supriya
Jones, Betsy A.
Rowlinson, Marie-Claire
Jaimon, Roshni
Onderko, Pennelyn
Darnall, Elaine
Gomez, Maria E.
Peloquin, Charles
Ashkin, David
Goswami, Neela D.
author_facet Haley, Connie A.
Macias, Patricia
Jasuja, Supriya
Jones, Betsy A.
Rowlinson, Marie-Claire
Jaimon, Roshni
Onderko, Pennelyn
Darnall, Elaine
Gomez, Maria E.
Peloquin, Charles
Ashkin, David
Goswami, Neela D.
author_sort Haley, Connie A.
collection PubMed
description The US Food and Drug Administration approved a 6-month regimen of pretomanid, bedaquiline, and linezolid for extensively drug-resistant or multidrug-intolerant tuberculosis after a trial in South Africa demonstrated 90% effectiveness 6 months posttreatment. We report on a patient who completed the regimen using a lower linezolid dose.
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spelling pubmed-77745822021-01-01 Novel 6-Month Treatment for Drug-Resistant Tuberculosis, United States Haley, Connie A. Macias, Patricia Jasuja, Supriya Jones, Betsy A. Rowlinson, Marie-Claire Jaimon, Roshni Onderko, Pennelyn Darnall, Elaine Gomez, Maria E. Peloquin, Charles Ashkin, David Goswami, Neela D. Emerg Infect Dis Research Letter The US Food and Drug Administration approved a 6-month regimen of pretomanid, bedaquiline, and linezolid for extensively drug-resistant or multidrug-intolerant tuberculosis after a trial in South Africa demonstrated 90% effectiveness 6 months posttreatment. We report on a patient who completed the regimen using a lower linezolid dose. Centers for Disease Control and Prevention 2021-01 /pmc/articles/PMC7774582/ /pubmed/33227229 http://dx.doi.org/10.3201/eid2701.203766 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Haley, Connie A.
Macias, Patricia
Jasuja, Supriya
Jones, Betsy A.
Rowlinson, Marie-Claire
Jaimon, Roshni
Onderko, Pennelyn
Darnall, Elaine
Gomez, Maria E.
Peloquin, Charles
Ashkin, David
Goswami, Neela D.
Novel 6-Month Treatment for Drug-Resistant Tuberculosis, United States
title Novel 6-Month Treatment for Drug-Resistant Tuberculosis, United States
title_full Novel 6-Month Treatment for Drug-Resistant Tuberculosis, United States
title_fullStr Novel 6-Month Treatment for Drug-Resistant Tuberculosis, United States
title_full_unstemmed Novel 6-Month Treatment for Drug-Resistant Tuberculosis, United States
title_short Novel 6-Month Treatment for Drug-Resistant Tuberculosis, United States
title_sort novel 6-month treatment for drug-resistant tuberculosis, united states
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774582/
https://www.ncbi.nlm.nih.gov/pubmed/33227229
http://dx.doi.org/10.3201/eid2701.203766
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