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Hospitalization for Invasive Pneumococcal Diseases in Young Children before Use of 13-Valent Pneumococcal Conjugate Vaccine, Suzhou, China

A 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease (IPD) was introduced in China in April 2017. We describe 105 children <5 years of age who were hospitalized for IPD at Soochow University Affiliated Children’s Hospital in Suzhou, China, during January 2010–December...

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Autores principales: Chen, Kaile, Zhang, Xiyan, Tao, Yunzhen, Wang, Yunzhong, Xue, Jian, Liu, Changpeng, Feng, Shuang, Yan, Yongdong, Chen, Qinghui, Tian, Jianmei, Zhao, Genming, Shao, Xuejun, Zhang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774583/
https://www.ncbi.nlm.nih.gov/pubmed/33350921
http://dx.doi.org/10.3201/eid2701.181415
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author Chen, Kaile
Zhang, Xiyan
Tao, Yunzhen
Wang, Yunzhong
Xue, Jian
Liu, Changpeng
Feng, Shuang
Yan, Yongdong
Chen, Qinghui
Tian, Jianmei
Zhao, Genming
Shao, Xuejun
Zhang, Tao
author_facet Chen, Kaile
Zhang, Xiyan
Tao, Yunzhen
Wang, Yunzhong
Xue, Jian
Liu, Changpeng
Feng, Shuang
Yan, Yongdong
Chen, Qinghui
Tian, Jianmei
Zhao, Genming
Shao, Xuejun
Zhang, Tao
author_sort Chen, Kaile
collection PubMed
description A 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease (IPD) was introduced in China in April 2017. We describe 105 children <5 years of age who were hospitalized for IPD at Soochow University Affiliated Children’s Hospital in Suzhou, China, during January 2010–December 2017. We calculated the incidence of hospitalization for IPD as 14.55/100,000 children in Suzhou. We identified 8 different capsular serotypes: 6B (28.4% of cases), 14 (18.9% of cases), 19A (18.9% of cases), 19F (12.2% of cases), 23F (10.8% of cases), 20 (4.1% of cases), 9V (4.1% of cases), and 15B/C (2.7% of cases). These results provide baseline data of IPD before the introduction of this vaccine in China, enabling researchers to better understand its effects on IPD incidence.
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spelling pubmed-77745832021-01-01 Hospitalization for Invasive Pneumococcal Diseases in Young Children before Use of 13-Valent Pneumococcal Conjugate Vaccine, Suzhou, China Chen, Kaile Zhang, Xiyan Tao, Yunzhen Wang, Yunzhong Xue, Jian Liu, Changpeng Feng, Shuang Yan, Yongdong Chen, Qinghui Tian, Jianmei Zhao, Genming Shao, Xuejun Zhang, Tao Emerg Infect Dis Research A 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease (IPD) was introduced in China in April 2017. We describe 105 children <5 years of age who were hospitalized for IPD at Soochow University Affiliated Children’s Hospital in Suzhou, China, during January 2010–December 2017. We calculated the incidence of hospitalization for IPD as 14.55/100,000 children in Suzhou. We identified 8 different capsular serotypes: 6B (28.4% of cases), 14 (18.9% of cases), 19A (18.9% of cases), 19F (12.2% of cases), 23F (10.8% of cases), 20 (4.1% of cases), 9V (4.1% of cases), and 15B/C (2.7% of cases). These results provide baseline data of IPD before the introduction of this vaccine in China, enabling researchers to better understand its effects on IPD incidence. Centers for Disease Control and Prevention 2021-01 /pmc/articles/PMC7774583/ /pubmed/33350921 http://dx.doi.org/10.3201/eid2701.181415 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Chen, Kaile
Zhang, Xiyan
Tao, Yunzhen
Wang, Yunzhong
Xue, Jian
Liu, Changpeng
Feng, Shuang
Yan, Yongdong
Chen, Qinghui
Tian, Jianmei
Zhao, Genming
Shao, Xuejun
Zhang, Tao
Hospitalization for Invasive Pneumococcal Diseases in Young Children before Use of 13-Valent Pneumococcal Conjugate Vaccine, Suzhou, China
title Hospitalization for Invasive Pneumococcal Diseases in Young Children before Use of 13-Valent Pneumococcal Conjugate Vaccine, Suzhou, China
title_full Hospitalization for Invasive Pneumococcal Diseases in Young Children before Use of 13-Valent Pneumococcal Conjugate Vaccine, Suzhou, China
title_fullStr Hospitalization for Invasive Pneumococcal Diseases in Young Children before Use of 13-Valent Pneumococcal Conjugate Vaccine, Suzhou, China
title_full_unstemmed Hospitalization for Invasive Pneumococcal Diseases in Young Children before Use of 13-Valent Pneumococcal Conjugate Vaccine, Suzhou, China
title_short Hospitalization for Invasive Pneumococcal Diseases in Young Children before Use of 13-Valent Pneumococcal Conjugate Vaccine, Suzhou, China
title_sort hospitalization for invasive pneumococcal diseases in young children before use of 13-valent pneumococcal conjugate vaccine, suzhou, china
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774583/
https://www.ncbi.nlm.nih.gov/pubmed/33350921
http://dx.doi.org/10.3201/eid2701.181415
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