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Asymmetric Graves’ Orbitopathy
Graves’ Orbitopathy (GO) is an autoimmune orbital disorder usually presenting as a sequala of autoimmune thyroid disease. The presence of GO is associated with increased psychological burden and, in severe cases may cause blindness. While most patients with GO present with bilateral disease, asymmet...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774639/ https://www.ncbi.nlm.nih.gov/pubmed/33391188 http://dx.doi.org/10.3389/fendo.2020.611845 |
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author | Panagiotou, Grigorios Perros, Petros |
author_facet | Panagiotou, Grigorios Perros, Petros |
author_sort | Panagiotou, Grigorios |
collection | PubMed |
description | Graves’ Orbitopathy (GO) is an autoimmune orbital disorder usually presenting as a sequala of autoimmune thyroid disease. The presence of GO is associated with increased psychological burden and, in severe cases may cause blindness. While most patients with GO present with bilateral disease, asymmetric or unilateral GO may affect a significant proportion of patients diagnosed with GO. Older age, male sex, active and severe disease correlate with asymmetric disease. However, the exact mechanisms causing asymmetry remain elusive. Herein, we review the literature on asymmetric GO and highlight its differences compared with bilateral GO. |
format | Online Article Text |
id | pubmed-7774639 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77746392021-01-01 Asymmetric Graves’ Orbitopathy Panagiotou, Grigorios Perros, Petros Front Endocrinol (Lausanne) Endocrinology Graves’ Orbitopathy (GO) is an autoimmune orbital disorder usually presenting as a sequala of autoimmune thyroid disease. The presence of GO is associated with increased psychological burden and, in severe cases may cause blindness. While most patients with GO present with bilateral disease, asymmetric or unilateral GO may affect a significant proportion of patients diagnosed with GO. Older age, male sex, active and severe disease correlate with asymmetric disease. However, the exact mechanisms causing asymmetry remain elusive. Herein, we review the literature on asymmetric GO and highlight its differences compared with bilateral GO. Frontiers Media S.A. 2020-12-17 /pmc/articles/PMC7774639/ /pubmed/33391188 http://dx.doi.org/10.3389/fendo.2020.611845 Text en Copyright © 2020 Panagiotou and Perros http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Endocrinology Panagiotou, Grigorios Perros, Petros Asymmetric Graves’ Orbitopathy |
title | Asymmetric Graves’ Orbitopathy |
title_full | Asymmetric Graves’ Orbitopathy |
title_fullStr | Asymmetric Graves’ Orbitopathy |
title_full_unstemmed | Asymmetric Graves’ Orbitopathy |
title_short | Asymmetric Graves’ Orbitopathy |
title_sort | asymmetric graves’ orbitopathy |
topic | Endocrinology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774639/ https://www.ncbi.nlm.nih.gov/pubmed/33391188 http://dx.doi.org/10.3389/fendo.2020.611845 |
work_keys_str_mv | AT panagiotougrigorios asymmetricgravesorbitopathy AT perrospetros asymmetricgravesorbitopathy |