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Asymmetric Graves’ Orbitopathy

Graves’ Orbitopathy (GO) is an autoimmune orbital disorder usually presenting as a sequala of autoimmune thyroid disease. The presence of GO is associated with increased psychological burden and, in severe cases may cause blindness. While most patients with GO present with bilateral disease, asymmet...

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Detalles Bibliográficos
Autores principales: Panagiotou, Grigorios, Perros, Petros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774639/
https://www.ncbi.nlm.nih.gov/pubmed/33391188
http://dx.doi.org/10.3389/fendo.2020.611845
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author Panagiotou, Grigorios
Perros, Petros
author_facet Panagiotou, Grigorios
Perros, Petros
author_sort Panagiotou, Grigorios
collection PubMed
description Graves’ Orbitopathy (GO) is an autoimmune orbital disorder usually presenting as a sequala of autoimmune thyroid disease. The presence of GO is associated with increased psychological burden and, in severe cases may cause blindness. While most patients with GO present with bilateral disease, asymmetric or unilateral GO may affect a significant proportion of patients diagnosed with GO. Older age, male sex, active and severe disease correlate with asymmetric disease. However, the exact mechanisms causing asymmetry remain elusive. Herein, we review the literature on asymmetric GO and highlight its differences compared with bilateral GO.
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spelling pubmed-77746392021-01-01 Asymmetric Graves’ Orbitopathy Panagiotou, Grigorios Perros, Petros Front Endocrinol (Lausanne) Endocrinology Graves’ Orbitopathy (GO) is an autoimmune orbital disorder usually presenting as a sequala of autoimmune thyroid disease. The presence of GO is associated with increased psychological burden and, in severe cases may cause blindness. While most patients with GO present with bilateral disease, asymmetric or unilateral GO may affect a significant proportion of patients diagnosed with GO. Older age, male sex, active and severe disease correlate with asymmetric disease. However, the exact mechanisms causing asymmetry remain elusive. Herein, we review the literature on asymmetric GO and highlight its differences compared with bilateral GO. Frontiers Media S.A. 2020-12-17 /pmc/articles/PMC7774639/ /pubmed/33391188 http://dx.doi.org/10.3389/fendo.2020.611845 Text en Copyright © 2020 Panagiotou and Perros http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Panagiotou, Grigorios
Perros, Petros
Asymmetric Graves’ Orbitopathy
title Asymmetric Graves’ Orbitopathy
title_full Asymmetric Graves’ Orbitopathy
title_fullStr Asymmetric Graves’ Orbitopathy
title_full_unstemmed Asymmetric Graves’ Orbitopathy
title_short Asymmetric Graves’ Orbitopathy
title_sort asymmetric graves’ orbitopathy
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774639/
https://www.ncbi.nlm.nih.gov/pubmed/33391188
http://dx.doi.org/10.3389/fendo.2020.611845
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