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Continuous versus pulsed microwave ablation in the liver: any difference in intraoperative pain scores?

BACKGROUND: This study prospectively compared intraoperative pain scores during percutaneous microwave ablation of the liver in patients randomized between continuous and pulsed energy delivery algorithms. METHODS: During a 12-month period, 20 patients who underwent microwave liver ablation were pro...

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Autores principales: Filippiadis, Dimitrios, Mazioti, Argyro, Velonakis, George, Tsochantzis, Athanasios, Tosoratti, Nevio, Kelekis, Alexis, Kelekis, Nikolaos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hellenic Society of Gastroenterology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774668/
https://www.ncbi.nlm.nih.gov/pubmed/33414626
http://dx.doi.org/10.20524/aog.2020.0557
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author Filippiadis, Dimitrios
Mazioti, Argyro
Velonakis, George
Tsochantzis, Athanasios
Tosoratti, Nevio
Kelekis, Alexis
Kelekis, Nikolaos
author_facet Filippiadis, Dimitrios
Mazioti, Argyro
Velonakis, George
Tsochantzis, Athanasios
Tosoratti, Nevio
Kelekis, Alexis
Kelekis, Nikolaos
author_sort Filippiadis, Dimitrios
collection PubMed
description BACKGROUND: This study prospectively compared intraoperative pain scores during percutaneous microwave ablation of the liver in patients randomized between continuous and pulsed energy delivery algorithms. METHODS: During a 12-month period, 20 patients who underwent microwave liver ablation were prospectively randomized between 2 different energy delivery modes: “continuous mode” (CM, n=10) and “pulsed mode” (PM, n=10). All ablation sessions were performed using the same microwave ablation platform under computed tomographic guidance and intravenous analgesia. Within 30 min post ablation, all patients completed a questionnaire assigning a numeric pain intensity score from 0 (no pain) to 10. RESULTS: Mean pain scores were 8.17±1.850 in the CM group and 4.50±1.567 in the PM group, with a statistically significant difference of 3.667±2.807 pain units (P=0.001). The mean procedure time was 53.5±20.90 min in the PM group vs. 58.5±17.44 min in the CM group (P=0.279). The mean size of the lesions was 2.81±0.95 cm in the PM group and 2.81±0.85 cm in the CM group (P=0.984). On a per-lesion basis, technical success was achieved in all evaluable tumors in both groups. No difference was noted in the local tumor control on the 6-month imaging evaluation. No complications were observed in the CM arm, while small perihepatic hemorrhagic fluid collections were reported in the PM group. CONCLUSIONS: Both algorithms for microwave energy delivery have comparable treatment effects in terms of 6-month local tumor control for liver lesions <3 cm in diameter. PM treatments compared to CM appear to induce significantly less pain in patients undergoing percutaneous liver ablation under intravenous analgesia.
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spelling pubmed-77746682021-01-06 Continuous versus pulsed microwave ablation in the liver: any difference in intraoperative pain scores? Filippiadis, Dimitrios Mazioti, Argyro Velonakis, George Tsochantzis, Athanasios Tosoratti, Nevio Kelekis, Alexis Kelekis, Nikolaos Ann Gastroenterol Original Article BACKGROUND: This study prospectively compared intraoperative pain scores during percutaneous microwave ablation of the liver in patients randomized between continuous and pulsed energy delivery algorithms. METHODS: During a 12-month period, 20 patients who underwent microwave liver ablation were prospectively randomized between 2 different energy delivery modes: “continuous mode” (CM, n=10) and “pulsed mode” (PM, n=10). All ablation sessions were performed using the same microwave ablation platform under computed tomographic guidance and intravenous analgesia. Within 30 min post ablation, all patients completed a questionnaire assigning a numeric pain intensity score from 0 (no pain) to 10. RESULTS: Mean pain scores were 8.17±1.850 in the CM group and 4.50±1.567 in the PM group, with a statistically significant difference of 3.667±2.807 pain units (P=0.001). The mean procedure time was 53.5±20.90 min in the PM group vs. 58.5±17.44 min in the CM group (P=0.279). The mean size of the lesions was 2.81±0.95 cm in the PM group and 2.81±0.85 cm in the CM group (P=0.984). On a per-lesion basis, technical success was achieved in all evaluable tumors in both groups. No difference was noted in the local tumor control on the 6-month imaging evaluation. No complications were observed in the CM arm, while small perihepatic hemorrhagic fluid collections were reported in the PM group. CONCLUSIONS: Both algorithms for microwave energy delivery have comparable treatment effects in terms of 6-month local tumor control for liver lesions <3 cm in diameter. PM treatments compared to CM appear to induce significantly less pain in patients undergoing percutaneous liver ablation under intravenous analgesia. Hellenic Society of Gastroenterology 2021 2020-11-20 /pmc/articles/PMC7774668/ /pubmed/33414626 http://dx.doi.org/10.20524/aog.2020.0557 Text en Copyright: © 2021 Hellenic Society of Gastroenterology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Filippiadis, Dimitrios
Mazioti, Argyro
Velonakis, George
Tsochantzis, Athanasios
Tosoratti, Nevio
Kelekis, Alexis
Kelekis, Nikolaos
Continuous versus pulsed microwave ablation in the liver: any difference in intraoperative pain scores?
title Continuous versus pulsed microwave ablation in the liver: any difference in intraoperative pain scores?
title_full Continuous versus pulsed microwave ablation in the liver: any difference in intraoperative pain scores?
title_fullStr Continuous versus pulsed microwave ablation in the liver: any difference in intraoperative pain scores?
title_full_unstemmed Continuous versus pulsed microwave ablation in the liver: any difference in intraoperative pain scores?
title_short Continuous versus pulsed microwave ablation in the liver: any difference in intraoperative pain scores?
title_sort continuous versus pulsed microwave ablation in the liver: any difference in intraoperative pain scores?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774668/
https://www.ncbi.nlm.nih.gov/pubmed/33414626
http://dx.doi.org/10.20524/aog.2020.0557
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