Cargando…

Comprehensive review of implications of COVID‐19 on clinical outcomes of cancer patients and management of solid tumors during the pandemic

Coronavirus disease‐2019 (COVID‐19) has emerged as a novel infection which has spread rapidly across the globe and currently presents a grave threat to the health of vulnerable patient populations like those with malignancy, elderly, and immunocompromised. Healthcare systems across the world are gra...

Descripción completa

Detalles Bibliográficos
Autores principales: Madan, Ankit, Siglin, Joshua, Khan, Aleem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774721/
https://www.ncbi.nlm.nih.gov/pubmed/33078903
http://dx.doi.org/10.1002/cam4.3534
_version_ 1783630321225302016
author Madan, Ankit
Siglin, Joshua
Khan, Aleem
author_facet Madan, Ankit
Siglin, Joshua
Khan, Aleem
author_sort Madan, Ankit
collection PubMed
description Coronavirus disease‐2019 (COVID‐19) has emerged as a novel infection which has spread rapidly across the globe and currently presents a grave threat to the health of vulnerable patient populations like those with malignancy, elderly, and immunocompromised. Healthcare systems across the world are grappling with the detrimental impact of this pandemic while learning about this novel disease and concurrently developing vaccines, strategies to mitigate its spread, and treat those infected. Cancer patients today face with a unique situation. They are susceptible to severe clinically adverse events and higher mortality from COVID‐19 infection as well as morbidity and mortality from their underlying malignancy. Conclusion: Our review suggests increased risk of mortality and serious clinical events from COVID‐19 infection in cancer patients. However, risk of adverse events does not seem to be increased by cancer therapies. True impact of COVID‐19 on cancer patients will unravel over the next few months. We have also reviewed clinical features of COVID‐19, recent recommendations from various medical, surgical, and radiation oncology societies for major solid tumor types like lung, breast, colorectal, and prostate cancer during the duration of this pandemic.
format Online
Article
Text
id pubmed-7774721
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-77747212021-01-05 Comprehensive review of implications of COVID‐19 on clinical outcomes of cancer patients and management of solid tumors during the pandemic Madan, Ankit Siglin, Joshua Khan, Aleem Cancer Med Clinical Cancer Research Coronavirus disease‐2019 (COVID‐19) has emerged as a novel infection which has spread rapidly across the globe and currently presents a grave threat to the health of vulnerable patient populations like those with malignancy, elderly, and immunocompromised. Healthcare systems across the world are grappling with the detrimental impact of this pandemic while learning about this novel disease and concurrently developing vaccines, strategies to mitigate its spread, and treat those infected. Cancer patients today face with a unique situation. They are susceptible to severe clinically adverse events and higher mortality from COVID‐19 infection as well as morbidity and mortality from their underlying malignancy. Conclusion: Our review suggests increased risk of mortality and serious clinical events from COVID‐19 infection in cancer patients. However, risk of adverse events does not seem to be increased by cancer therapies. True impact of COVID‐19 on cancer patients will unravel over the next few months. We have also reviewed clinical features of COVID‐19, recent recommendations from various medical, surgical, and radiation oncology societies for major solid tumor types like lung, breast, colorectal, and prostate cancer during the duration of this pandemic. John Wiley and Sons Inc. 2020-10-20 /pmc/articles/PMC7774721/ /pubmed/33078903 http://dx.doi.org/10.1002/cam4.3534 Text en © 2020 The Authors. Cancer Medicine published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Cancer Research
Madan, Ankit
Siglin, Joshua
Khan, Aleem
Comprehensive review of implications of COVID‐19 on clinical outcomes of cancer patients and management of solid tumors during the pandemic
title Comprehensive review of implications of COVID‐19 on clinical outcomes of cancer patients and management of solid tumors during the pandemic
title_full Comprehensive review of implications of COVID‐19 on clinical outcomes of cancer patients and management of solid tumors during the pandemic
title_fullStr Comprehensive review of implications of COVID‐19 on clinical outcomes of cancer patients and management of solid tumors during the pandemic
title_full_unstemmed Comprehensive review of implications of COVID‐19 on clinical outcomes of cancer patients and management of solid tumors during the pandemic
title_short Comprehensive review of implications of COVID‐19 on clinical outcomes of cancer patients and management of solid tumors during the pandemic
title_sort comprehensive review of implications of covid‐19 on clinical outcomes of cancer patients and management of solid tumors during the pandemic
topic Clinical Cancer Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774721/
https://www.ncbi.nlm.nih.gov/pubmed/33078903
http://dx.doi.org/10.1002/cam4.3534
work_keys_str_mv AT madanankit comprehensivereviewofimplicationsofcovid19onclinicaloutcomesofcancerpatientsandmanagementofsolidtumorsduringthepandemic
AT siglinjoshua comprehensivereviewofimplicationsofcovid19onclinicaloutcomesofcancerpatientsandmanagementofsolidtumorsduringthepandemic
AT khanaleem comprehensivereviewofimplicationsofcovid19onclinicaloutcomesofcancerpatientsandmanagementofsolidtumorsduringthepandemic