Overnight fasting before lapatinib administration to breast cancer patients leads to reduced toxicity compared with nighttime dosing: a retrospective cohort study from a randomized clinical trial

BACKGROUND: The bioavailability of lapatinib is affected by food, even following the 1 hour fast recommended by the package insert. We hypothesized that overnight fasting would minimize food‐drug interactions. Here, we investigated if lapatinib administration timing is associated with its tolerabili...

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Detalles Bibliográficos
Autores principales: Tsuda, Moe, Ishiguro, Hiroshi, Toriguchi, Naoko, Masuda, Norikazu, Bando, Hiroko, Ohgami, Masahiro, Homma, Masato, Morita, Satoshi, Yamamoto, Naohito, Kuroi, Katsumasa, Yanagita, Yasuhiro, Takano, Toshimi, Shimizu, Satoru, Toi, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774723/
https://www.ncbi.nlm.nih.gov/pubmed/33094919
http://dx.doi.org/10.1002/cam4.3528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774723/
https://www.ncbi.nlm.nih.gov/pubmed/33094919
http://dx.doi.org/10.1002/cam4.3528

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