Overnight fasting before lapatinib administration to breast cancer patients leads to reduced toxicity compared with nighttime dosing: a retrospective cohort study from a randomized clinical trial

BACKGROUND: The bioavailability of lapatinib is affected by food, even following the 1 hour fast recommended by the package insert. We hypothesized that overnight fasting would minimize food‐drug interactions. Here, we investigated if lapatinib administration timing is associated with its tolerabili...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsuda, Moe, Ishiguro, Hiroshi, Toriguchi, Naoko, Masuda, Norikazu, Bando, Hiroko, Ohgami, Masahiro, Homma, Masato, Morita, Satoshi, Yamamoto, Naohito, Kuroi, Katsumasa, Yanagita, Yasuhiro, Takano, Toshimi, Shimizu, Satoru, Toi, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7774723/
https://www.ncbi.nlm.nih.gov/pubmed/33094919
http://dx.doi.org/10.1002/cam4.3528

Ejemplares similares

Ejemplares similares